原著論文

Tachikawa M, Hosoya K, Terasaki T.
Pharmacological significance of prostaglandin e2 and d2 transport at the brain barriers.
Adv Pharmacol. 2014;71:337-60.

Kubo Y, Tsuchiyama A, Shimizu Y, Akanuma S, Hosoya K.
Involvement of carrier-mediated transport in the retinal uptake of clonidine at the inner blood-retinal barrier.
Mol Pharm. 2014 Oct 6;11(10):3747-53.

Akanuma S, Higuchi T, Higashi H, Ozeki G, Tachikawa M, Kubo Y, Hosoya K.
Transporter-mediated Prostaglandin E2 Elimination across the Rat Blood-brain Barrier and Its Attenuation by the Activation of N-methyl-D-aspartate Receptors.
Drug Metab Pharmacokinet. 2014 Oct 25;29(5):387-93.

Fujii S, Setoguchi C, Kawazu K, Hosoya K.
Impact of P-glycoprotein on blood-retinal barrier permeability: comparison of blood-aqueous humor and blood-brain barrier using mdr1a knockout rats.
Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8.

Eskilsson A, Tachikawa M, Hosoya K, Blomqvist A.
Distribution of microsomal prostaglandin E synthase-1 in the mouse brain.
J Comp Neurol. 2014 Dec 1;522(14):3229-44.

Kubo Y, Tomise A, Tsuchiyama A, Akanuma SI, Hosoya KI.
Involvement of the carrier-mediated process in the retina-to-blood transport of spermine at the inner blood-retinal barrier.
Exp Eye Res. 2014 May 14;124:17-23.

Yahara T, Tachikawa M, Akanuma S, Kubo Y, Hosoya K.
Amino Acid Residues Involved in the Substrate Specificity of TauT/SLC6A6 for Taurine and γ-Aminobutyric Acid.
Biol Pharm Bull. 2014;37(5):817-25.

Hosoya K, Inoue K.
The cutting-edge of clinical therapeutics based on pharmacokinetic/pharmacodynamic theory. Preface.
Drug Metab Pharmacokinet. 2014;29(1):3.

Kasai Y, Akanuma S, Kubo Y, Tachikawa M, Hosoya K.
Pharmacokinetics of guanidinosuccinic acid in rat blood and cerebrospinal fluid.
Drug Metab Pharmacokinet. 2014;29(1):97-100.

Salomon JJ, Ehrhardt C, Hosoya K.
The verapamil transporter expressed in human alveolar epithelial cells (A549) does not interact with β2-receptor agonists.
Drug Metab Pharmacokinet. 2014;29(1):101-4.