研究業績
原著論文
Perrone L, Devi TS, Hosoya KI, Terasaki T, Singh LP.
Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy.
Cell Death Dis. 2010 Aug 19;1:e65.
Adachi T, Yasuda H, Aida K, Kamiya T, Hara H, Hosoya K, Terasaki T, Ikeda T.
Regulation of extracellular-superoxide dismutase in rat retina pericytes.
Redox Rep. 2010;15(6):250-8.
Yahara T, Tachikawa M, Akanuma S, Hosoya K.
Hypertonicity enhances GABA uptake by cultured rat retinal capillary endothelial cells.
Drug Metab Pharmacokinet. 2010;25(6):611-5.
Hosoya K, Yamamoto A, Akanuma S, Tachikawa M.
Lipophilicity and transporter influence on blood-retinal barrier permeability: a comparison with blood-brain barrier permeability.
Pharm Res. 2010 Dec;27(12):2715-24.
Ohkura Y, Akanuma S, Tachikawa M, Hosoya K.
Blood-to-retina transport of biotin via Na+-dependent multivitamin transporter (SMVT) at the inner blood-retinal barrier.
Exp Eye Res. 2010 Sep;91(3):387-92.
Hosoya K, Ichikawa T, Akanuma S, Hirose S, Tachikawa M.
Glycine and L-arginine transport in cultured Müller glial cells (TR-MUL).
Neurochem Int. 2010 Oct;57(3):262-8.
Tomi M, Hosoya K.
The role of blood-ocular barrier transporters in retinal drug disposition: an overview.
Expert Opin Drug Metab Toxicol. 2010 Sep;6(9):1111-24.
Akanuma S, Hosoya K, Ito S, Tachikawa M, Terasaki T, Ohtsuki S.
Involvement of multidrug resistance-associated protein 4 in efflux transport of prostaglandin E(2) across mouse blood-brain barrier and its inhibition by intravenous administration of cephalosporins.
J Pharmacol Exp Ther. 2010 Jun;333(3):912-9.
Yoneyama D, Shinozaki Y, Lu WL, Tomi M, Tachikawa M, Hosoya K.
Involvement of system A in the retina-to-blood transport of l-proline across the inner blood-retinal barrier.
Exp Eye Res. 2010 Apr;90(4):507-13.
Yamamoto A, Akanuma S, Tachikawa M, Hosoya K.
Involvement of LAT1 and LAT2 in the high- and low-affinity transport of L-leucine in human retinal pigment epithelial cells (ARPE-19 cells).
J Pharm Sci. 2010 May;99(5):2475-82.
Tachikawa M, Takeda Y, Tomi M, Hosoya K.
Involvement of OCTN2 in the transport of acetyl-L-carnitine across the inner blood-retinal barrier.
Invest Ophthalmol Vis Sci. 2010 Jan;51(1):430-6.
著書・総説
Tomi M., and Hosoya K.: The role of blood-ocular barrier transporters in retinal drug disposition: an overview. Expert. Opin. Drug Metab. Toxicol., 9: 1111-1124, 2010.