研究業績
原著論文
Ohtsuki S, Ikeda C, Uchida Y, Sakamoto Y, Miller F, Glacial F, Decleves X, Scherrmann JM, Couraud PO, Kubo Y, Tachikawa M, Terasaki T.
Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.
Mol Pharm. 2013;10:289-96.
Akanuma S, Hirose S, Tachikawa M, Hosoya K.
Localization of organic anion transporting polypeptide (Oatp) 1a4 and Oatp1c1 at the rat blood-retinal barrier.
Fluids Barriers CNS. 2013 Oct 2;10(1):29.
Usui T, Kubo Y, Akanuma S, Hosoya K.
β-alanine and l-histidine transport across the inner blood-retinal barrier: potential involvement in L-carnosine supply.
Exp Eye Res. 2013 Aug;113:135-42.
Kubo Y, Shimizu Y, Kusagawa Y, Akanuma S, Hosoya K.
Propranolol transport across the inner blood-retinal barrier: potential involvement of a novel organic cation transporter.
J Pharm Sci. 2013 Sep;102(9):3332-42.
Devi TS, Hosoya K, Terasaki T, Singh LP.
Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: implications for diabetic retinopathy.
Exp Cell Res. 2013 Apr 15;319(7):1001-12.
Akanuma S, Soutome T, Hisada E, Tachikawa M, Kubo Y, Hosoya K.
Na+-independent nucleoside transporters regulate adenosine and hypoxanthine levels in Müller cells and the inner blood-retinal barrier.
Invest Ophthalmol Vis Sci. 2013 Feb 27;54(2):1469-77.
Tega Y, Akanuma S, Kubo Y, Terasaki T, Hosoya K.
Blood-to-brain influx transport of nicotine at the rat blood-brain barrier: involvement of a pyrilamine-sensitive organic cation transport process.
Neurochem Int. 2013 Jan;62(2):173-81.
Kubo Y, Kusagawa Y, Tachikawa M, Akanuma S, Hosoya K.
Involvement of a novel organic cation transporter in verapamil transport across the inner blood-retinal barrier.
Pharm Res. 2013 Mar;30(3):847-56.
著書・総説
久保義行,赤沼伸乙,細谷健一: カチオン性薬物輸送に見る血液網膜関門と血液脳関門の類似と相違.細胞工学.2013;32:950-4.
立川正憲,赤沼伸乙,寺崎哲也: 脳関門プロスタグランジン輸送の分子病態生理.細胞工学.2013;32:946-9