Laboratory of Biopharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama

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Publications

Fujii S, Setoguchi C, Kawazu K, Hosoya K.
Functional Characterization of Carrier-Mediated Transport of Pravastatin across the Blood-Retinal Barrier in Rats.
Drug Metab Dispos. 2015 Dec;43(12):1956-9.

Kubo Y, Obata A, Akanuma S, Hosoya K.
Impact of Cationic Amino Acid Transporter 1 on Blood-Retinal Barrier Transport of L-Ornithine.
Invest Ophthalmol Vis Sci. 2015 Sep 1;56(10):5925-32.

Salomon JJ, Gausterer JC, Yahara T, Hosoya K, Huwer H, Hittinger M, Schneider-Daum N, Lehr CM, Ehrhardt C.
Organic cation transporter function in different in vitro models of human lung epithelium.
Eur J Pharm Sci. 2015 Dec 1;80:82-8.

Tega Y, Kubo Y, Yuzurihara C, Akanuma S, Hosoya K.
Carrier-Mediated Transport of Nicotine Across the Inner Blood-Retinal Barrier: Involvement of a Novel Organic Cation Transporter Driven by an Outward H(+) Gradient.
J Pharm Sci. 2015 Sep;104(9):3069-75.

Salomon JJ, Hagos Y, Petzke S, Kühne A, Gausterer JC, Hosoya K, Ehrhardt C.
Beta-2 Adrenergic Agonists Are Substrates and Inhibitors of Human Organic Cation Transporter 1.
Mol Pharm. 2015 Aug 3;12(8):2633-41.

Sakurai T, Akanuma S, Usui T, Kubo Y, Tachikawa M, Hosoya K.
Excitatory Amino Acid Transporter 1-Mediated L-Glutamate Transport at the Inner Blood-Retinal Barrier: Possible Role in L-Glutamate Elimination from the Retina.
Biol Pharm Bull. 2015;38(7):1087-91.

Akanuma S, Zakoji N, Kubo Y, Hosoya K.
In vitro study of L-glutamate and L-glutamine transport in retinal pericytes: involvement of excitatory amino Acid transporter 1 and alanine-serine-cysteine transporter 2.
Biol Pharm Bull. 2015;38(6):901-8.

Akanuma SI, Sakurai T, Tachikawa M, Kubo Y, Hosoya KI.
Transporter-mediated L-glutamate elimination from cerebrospinal fluid: possible involvement of excitatory amino acid transporters expressed in ependymal cells and choroid plexus epithelial cells.
Fluids Barriers CNS. 2015 Apr 29;12(1):11.

Nakanishi T, Hasegawa Y, Mimura R, Wakayama T, Uetoko Y, Komori H, Akanuma SI, Hosoya KI, Tamai I.
Prostaglandin Transporter (PGT/SLCO2A1) Protects the Lung from Bleomycin-Induced Fibrosis.
PLoS One. 2015 Apr 29;10(4):e0123895.

Zakoji N, Akanuma S, Tachikawa M, Hosoya K.
Involvement of cationic amino Acid transporter 1 in L-arginine transport in rat retinal pericytes.
Biol Pharm Bull. 2015;38(2):257-62.

Kaneko Y, Tachikawa M, Akaogi R, Fujimoto K, Ishibashi M, Uchida Y, Couraud PO, Ohtsuki S, Hosoya K, Terasaki T.
Contribution of pannexin 1 and connexin 43 hemichannels to extracellular calcium-dependent transport dynamics in human blood-brain barrier endothelial cells.
J Pharmacol Exp Ther. 2015 Apr;353(1):192-200.

Tega Y, Akanuma S, Kubo Y, Hosoya K.
Involvement of the h+/organic cation antiporter in nicotine transport in rat liver.
Drug Metab Dispos. 2015 Jan;43(1):89-92.

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Laboratory of Biopharmaceutics
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