Laboratory of Biopharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama

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    • before 2000
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Publications

Articles

Hosoya KI, Takashima T, Tetsuka K, Nagura T, Ohtsuki S, Takanaga H, Ueda M, Yanai N, Obinata M, Terasaki T.
mRNA expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting.
J Drug Target. 2000;8(6):357-70.

Hosoya KI, Horibe Y, Kim KJ, Lee VH.
Carrier-mediated transport of NG-nitro-L-arginine, a nitric oxide synthase inhibitor, in the pigmented rabbit conjunctiva.
J Pharmacol Exp Ther. 1998 Apr;285(1):223-7.

Hosoya KI, Kim KJ, Lee VH.
Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers.
Pharm Res. 1996 Jun;13(6):885-90.

Books and Reviews

Terasaki T.,Ohtsuki S.,Takanaga H.,Testuka K.,Nagase K.,Wakayama K.,Osawa I.,Yanai N.,Obinata M.,Kikuchi A.,Okano T.,and Hosoya K.: Brain barrier function: its analysis and reconstitution,In Tissue Engi-neering for Therapeutic Use 4,by Ikeda K.,and Shimizu Y.(Ed.),95-104,Elsevier,Amsterdam,2000.

高長ひとみ,森しのぶ,徳田典代,大槻純男,細谷健一,寺崎哲也: 薬物動態を決定する機能蛋白質: 血液脳関門と血液脳脊髄液関門. 月刊薬事, 42: 761-776, 2000.

小泉保: 薬物生体内挙動と薬物反応の速度論的解析. 薬学雑誌, 120: 445-454, 2000.

Hatanaka T.: Clinical pharmacokinetics of pravastatin: Mechanisms of pharmacokinetic events. Clin. Pharmacokin.,39: 397-412,2000.

T. Terasaki, K. Hosoya: The blood-brain barrier efflux transporters as a detoxifying system for the brain, Adv. Drug Deliv. Rev., 36, 195-209, 1999.

T. Terasaki, K. Hosoya: The brain efflux index method(BEI) IN: Brain barrier Systems, Alfred Benzon Symposium 45, O.B. Paulson, G.M. Knudsen, T. Moos(Ed), Munksgaard, Copenhagen, 114-123, 1999.

寺崎哲也,細谷健一: 血液脳関門研究における最近の進歩. 薬事新報, 2050, 331-337, 1999.

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Laboratory of Biopharmaceutics
2630 Sugitani, Toyama-shi 930-0194, Phone: 81-76-434-7505

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