生体認識化学研究室

Laboratory of Biorecognition Chemistry

研究業績 The Publication List

原著論文 Articles

 
2024
Fluorescent Labeling of a Target Protein with an Alkyl Diazirine Photocrosslinker Bearing a Cinnamate Moiety
Taikai Nakashima, Takumi Iwanabe, Hiroki Tanimoto, Takenori Tomohiro
Chem. Asian J. 2024, XX(XX), XX-XX. (DOI: 10.1002/asia.202400288)

Synthesis of Naphthalimide Azocarboxylates Showing Turn-on Fluorescence by Substitution Reaction With Sulfinates
Hiroki Tanimoto, Shogo Kyogaku, Aoi Otsuki, Takenori Tomohiro
Chem. Asian J. 2024, XX(XX), XX-XX. (DOI: 10.1002/asia.202400145)

Amphos-Mediated Conversion of Alkyl Azides to Diazo Compounds and One-Pot Azide-Site Selective Transient Protection, Click Conjugation, and Deprotective Transformation
Hiroki Tanimoto, Ryo Adachi, Kodai Tanisawa, Takenori Tomohiro
Org. Lett. 2024, 26(12), 2409-2413. (DOI: 10.10.1021/acs.orglett.4c00566)

2023
Synthesis, α-Glucosidase Inhibitory Activity and Molecular Docking Study of Chalcone Derivatives Bearing a 1H-1,2,3-Triazole Unit
Bayu Ardiansah, Nur Rohman, Mochammad Arfin Fardiansyah Nasution, Hiroki Tanimoto, Antonius Herry Cahyana, Arif Fadlan, Titin Ariyani
Chem. Pharm. Bull. 2023, 71(5), 520-533. (Open Access) (DOI: 10.1248/cpb.c22-00844)

2022
Neighboring Nitrogen Atom-Induced Reactions of Azidoacetyl Hydrazides, Including Unexpected Nitrogen-Nitrogen Bond Cleavage of the Hydrazide
Hiroki Tanimoto, Ryo Adachi, Aoi Otsuki, Takenori Tomohiro
Organics 2022, 3(4), 520-533. (Open Access) (DOI: 10.3390/org3040035)

Concise Synthesis of the Terpene Core Structure of Suaveolindole Through a Time-Economic Route
Hiroki Tanimoto, Kazuki Tojo, Tsumoru Morimoto, Kiyomi Kakiuchi
Synlett 2022, 33(3), 273-276. (DOI: 10.1055/a-1707-6593)

2021
Taming the Reactivity of Alkyl Azides by Intramolecular Hydrogen Bonding: Site-Selective Conjugation of Unhindered Diazides
Koshiro Maegawa, Hiroki Tanimoto, Seiji Onishi, Takenori Tomohiro, Tsumoru Morimoto, Kiyomi Kakiuchi
Org. Chem. Front. 2021, 8(20), 5793-5803. (Open Access) (DOI: 10.1039/D1QO01088C)

Sulfonium Ion-Promoted Traceless Schmidt Reaction of Alkyl Azides
Bayu Ardiansah, Hiroki Tanimoto, Takenori Tomohiro, Tsumoru Morimoto, Kiyomi Kakiuchi
Chem. Commun. 2021, 57(70), 8738-8741. (DOI: 10.1039/D1CC02770K)

The Lysosomal Protein ABCD4 can Transport Vitamin B12 Across Liposomal Membranes in vitro
Katsuki Kitai, Kosuke Kawaguchi, Takenori Tomohiro, Masashi Morita, Takanori So, Tsuneo Imanaka,
J. Biol. Chem. 2021, 296, 100654. (DOI: 10.1016/j.jbc.2021.100654)

Photodissociation of the Product from a Transition-Metal Center Allows the Catalytic Cycle to Proceed: The Rhodium(I)-Catalyzed [2+2+1] Carbonylative Cycloaddition of Diynes
JingWen Jia, Tsumoru Morimoto, Yoshiko Yamaguchi, Hiroki Tanimoto, Kiyomi Kakiuchi
Org. Lett. 2021, 23(12), 4893-4897. (DOI: 10.1021/acs.orglett.1c01631)

Rhodium(I)-Catalyzed CO Gas-Free Arylative Dual-Carbonylation of Alkynes with Arylboronic Acids via the Formyl C-H Activation of Formaldehyde
Tsumoru Morimoto, Chuang Wang, Hiroki Tanimoto, Levent Artok, Kiyomi Kakiuchi
Synthesis 2021, 53(18), 3372–3382. (DOI: 10.1055/a-1468-8377)

Synthesis of a Pentacoordinate Germanium Compound Possessing a γ-Lactone and a Dative-Bonding Carboxylic Acid
Hiroki Tanimoto, Daiki Toumori, Tsumoru Morimoto, Kiyomi Kakiuchi
Heterocycles 2021, 103(1), 465–475. (DOI: 10.3987/COM-20-S(K)9)

2020
Cationic Rhodium(I)-Catalyzed Carbonylative [2+2+1] Cycloaddition of Diynes
Tsumoru Morimoto, JingWen Jia, Yoshiko Yamaguchi, Hiroki Tanimoto, Kiyomi Kakiuchi,
Asian J. Org. Chem. 2020, 11(9), 1778–1782. (DOI: 10.1002/ajoc.202000436)

CO Gas-free Intramolecular Cyclocarbonylation Reactions of Haloarenes Having a C-Nucleophile through CO-Relay between Rhodium and Palladium
Tsumoru Morimoto, Mana Yamashita, Ai Tomiie, Hiroki Tanimoto, Kiyomi Kakiuchi
Chem. Asian J. 2020, 15(4), 473–477. (DOI: 10.1002/asia.201901595)

Synthesis, Characterization, and in vitro Antimalarial Activity of Dihydroxylation Derivatives of Triclosan
Wahyu Fitriana, Arry Yanuar, Ade Arsianti, Hiroki Tanimoto, Kiyomi Kakiuchi
Int. J. App. Pharm. 2020, 12(1), 56–59. (DOI: 10.22159/ijap.2020.v12s1.FF007)

Synthesis, Characterization, and Cytotoxicity Evaluation of Gallic Acid Nanoparticles Towards Breast T47D Cancer Cells
Ade Arsianti, Anton Bahtiar, Fadilah Fadilah, Vincent Kharisma Wangsaputra, Rafika Indah Paramita, Norma Nur Azizah, Lince Dameria Nadapdap, Ajeng Megawati Fajrin, Hiroki Tanimoto, Kiyomi Kakiuchi
Pharmacogn. J. 2020, 12(2), 321–327. (DOI: 10.5530/pj.2020.12.51)

Phytochemical Composition and Evaluation of Marine Algal Sargassum polycystum for Antioxidant Activity and In Vitro Cytotoxicity on Hela Cells
Ade Arsianti, Anton Bahtiar, Vincent Kharisma Wangsaputra, Norma Nur Azizah, Wilzar Fachri, Lince Dameria Nadapdap, Ajeng Megawati Fajrin, Hiroki Tanimoto, Kiyomi Kakiuchi
Pharmacogn. J. 2020, 12(1), 88–94. (DOI: 10.5530/pj.2020.12.14)

2019

Novel coupling reaction between sulfonyl azide and N,N,N',N'-tetramethylthiourea
M. Aswad, J. Chiba, Y. Hatanaka, T. Tomohiro
Tetrahedron Lett., 60, 1611-1613 (2019). DOI: 10.1016/j.tetlet.2019.05.029
 
Photoinduced electron transfer-regulated protein labeling with a coumarin-based multifunctional photocrosslinker
Y. Hotta, T. Kaneko, R. Hayashi, A. Yamamoto, S. Morimoto, J. Chiba, T. Tomohiro
Chem. Asian J., 14, 398-402 (2019). DOI: 10.1002/asia.201801673

Additive-free, enzymatic phosphorylation and ligation of artificial oligonucleotides composed of C-nucleosides at the reaction points
Y. Oda, J. Chiba, F. Kurosaki, Y. Yamade, M. Inouye
ChemBioChem, in press. DOI: 10.1002/cbic.201900217
 

2018

Multiple cellular transport and binding process of unesterified docosahexanoic acid in outer blood-retinal barrier retinal pigment epithelial cells
M. Tachikawa, S. Akanuma, T. Imai, S. Okayasu, T. Tomohiro, Y. Hatanaka, K. Hosoya
Biol. Pharm. Bull., 41, 1384-1392 (2018). DOI: 10.1248/bpb.b18-00185

Synthesis of alkynyl C-nucleotide triphosphates toward enzymatic elongation of artificial DNA
Y. Oda, J. Chiba, M. Inouye
Heterocycles, 97, 612-620 (2018). DOI: 10.3987/COM-18-S(T)48

Design and synthesis of a DNA-like structure composed of alkynyl C-nucleotide with 2-aminopyrimidin-4-one as a nucleobase
F. Kurosaki, J. Chiba, M. Inouye
Heterocycles, 97, 1149-1156 (2018). DOI: 10.3987/COM-18-S(T)53
 
 
2017
 
Simple synthesis of sulfonyl amidine-containing glucosidase inhibitors by a chemoselective coupling reaction between D-gluconothiolactam and sulfonyl azides
M. Aswad, J. Chiba, T. Tomohiro, Y. Hatanaka
Int. Res. J. Pure Appl. Chem., 14(2), 1-8 (2017). DOI: 10.9734/IRJPAC/2017/34259
 
 Behavioral impairment in SHATI/NAT8L knockout mice via dysfunction of myelination development
K. Sumi, K. Uno, H. Noike, T. Tomohiro, Y. Hatanaka, Y. Furukawa-Hibi, T. Nabeshima, Y. Miyamoto, A. Nitta
Sci. Rep., 7, 16872 (2017). DOI: 10.1038/s41598-017-17151-1
 
 
2016
 
Kinetic controlled affinity labeling of target enzyme with thioester chemistry
T. Tomohiro, M. Nakabayashi, Y. Sugita, S. Morimoto
Bioorg. Med. Chem., 24, 3336-3341 (2016). DOI: 10.1016/j.bmc.2016.05.059
 
Syndecan-4 is a receptor for clathrin-mediated endocytosis of arginine-rich cell-penetrating peptides
Y. Kawaguchi, T. Takeuchi, K. Kuwata, J. Chiba, Y. Hatanaka, I. Nakase, S. Futaki
Bioconjugate Chem., 27, 1119-1130 (2016). DOI: 10.1021/acs.bioconjchem.6b00082
 
Evaluation of dipole moment and electrophilicity on the nature of click-type coupling reaction between thioamide and sulfonyl azide 
M. Aswad, J. Chiba, T. Tomohiro, Y. Hatanaka
Tetrahedron Lett., 57, 1313-1316 (2016). DOI: 10.1016/j.tetlet.2016.02.028
 
 
2015
 
Structure-assisted ligand-binding analysis using fluorogenic photoaffinity labeling
S. Masuda, T. Tomohiro, S. Yamaguchi, S. Morimoto, Y. Hatanaka
Bioorg. Med. Chem. Lett., 25, 1675-1678 (2015). DOI: 10.1016/j.bmcl.2015.03.008
 
Third generation photo-cross-linked small-molecule affinity matrix: A photoactivatable and photocleavable system enabling quantitative analysis of the photo-cross-linked small molecules and their target purification
T. Suzuki, T. Okamura, T. Tomohiro, Y. Iwabuchi, N. Kanoh
Bioconjugate Chem., 26, 389-395 (2015). DOI: 10.102/bc500559e
 
A firmly hybridizable, DNA-like architecture with DAD/ADA- and ADD/DAA-type nonnatural base pairs as an extracellular genetic candidate
W. Shirato, J. Chiba, M. Inouye
Chem. Commun., 51, 7043-7046 (2015). DOI: 10.1039/C4CC09486G
 
Alternative one-pot synthesis of (trifluoromethyl)phenyldiazirines from tosyloxime derivatives: Application for new synthesis of optically pure diazirinylphenylalanines for photoaffinity labeling
L. Wang, Y. Murai, T. Yoshida, A. Ishida, K. Masuda, Y. Sakihama, Y. Hashidoko, Y. Hatanaka, M. Hashimoto
Org. Lett., 17, 616-619 (2015). DOI: 10.1021/ol503630z
 
Synthesis of photoreactive diazirinyl salicin derivative to elucidate functional analysis of the bitter taste receptor
M. Sakurai, T. Yoshida, L. Wang, Y. Murai, K. Masuda, Y. Sakihama, Y. Hashidoko, Y. Hatanaka, M. Hashimoto
Heterocycles, 90, 698-705 (2015). DOI: 10.3987/COM-14-S(K)36
 
 
2014
 
An isotope-coded fluorogenic cross-linker for high-performance target identification based on photoaffinity labeling 
T. Tomohiro, S. Morimoto, T. Shima, J. Chiba, Y. Hatanaka
Angew. Chem. Int. Ed., 53, 13502-13505 (2014). DOI: 10.1002/anie.201408580
 
Synthesis of methoxy-substituted diazirinyl phenylalanine -- A novel photoreactive asparatame derivative for functional analysis of sweet receptors
M. Sakurai, K. Masuda, L. Wang, Y. Murai, Y. Sakihama, Y. Hashidoko, Y. Hatanaka, M. Hashimoto
Heterocycles, 88, 629-637 (2014). DOI: 10.2987/COM-13-S(S)14
 
Hydrogen-deuterium exchange of cross-linkable alpha-amino acid derivatives in deuterated triflic acid
L. Wang, Y. Murai, T. Yoshida, M. Okamoto, K. Masuda, Y. Sakihama, Y. Hashidoko, Y. Hatanaka, M. Hashimoto
Biosci. Biotechnol. Biochem., 78, 1129-1134 (2014). DOI: 10.1080/09168451.2014.917267
 
Deformable nature of various damaged DNA duplexes estimated by an electrochemical analysis on electrodes
J. Chiba, S. Aoki, J. Yamamoto, S. Iwai, M. Inouye
Chem. Commun., 50, 11126-11128 (2014). DOI: 10.1039/C4CC04513K
 
 
2013
 
[3-(Trifluoromethyl)-3H-diazirin-3-yl]coumarin as a carbene-generating photocross-linker with masked fluorogenic beacon
T. Tomohiro, A. Yamamoto, Y. Tatsumi, Y. Hatanaka
Chem. Commun., 49, 11551-11553 (2013). DOI: 10.1039/C3CC45780J
 
Affinity-based fluorogenic labeling of ATP-binding proteins with sequential photoactivatable cross-linkers
T. Tomohiro, H. Inoguchi, S. Masuda, Y. Hatanaka
Bioorg. Med. Chem. Lett., 23, 5605-5608 (2013). DOI: 10.1016/j.bmcl.2013.08.041
  
Coupling reaction of thiosmides with sulfonyl azides: an efficient catalyst-free click-type ligation under mild conditions
M. Aswad, J. Chiba, T. Tomohiro, Y. Hatanaka
Chem. Commun., 49, 10242-1p244 (2013). DOI: 10.1039/C3CC46055J
 
Simple and stereocontrolled preparation of benzoylated phenylalanine using Friedel-Crafts reaction in trifluoromethanesulfonic acid for photoaffinity labeling
Y. Murai, L. Wang, Y. Muto, Y. Sakihama, Y. Hashidoko, Y. Hatanaka, M. Hashimoto
Heterocycles, 87, 2119-2126 (2013). DOI: 10.3987/COM-13-12815
 
Distinct metabolites for photoreactive L-phenylalanine derivatives in Klebsiella sp. CK6 isolated from Rhizosphere of a wild dipterocarp sapling
L. Wang, W. Hisano, Y. Murai, M. Sakurai, Y. Muto, H. Ikemoto, M. Okamoto, T. Murotani, R. Isoda, D. Kim, Y. Sakihama, I. R. Sitepu, Y. Hashidoko, Y. Hatanaka, M. Hashimoto
Molecules, 18, 8393-8401 (2013). DOI: 10.3390/molecules18078393
 
Rapid and controllable hydrogen/deuterium exchange on aromatic rings of alpha-amino acids and peptides
Y. Murai, L. Wang, K. Masuda, Y. Sakihama, Y. Hashidoko, Y. Hatanaka, M. Hashimoto
Eur. J. Org. Chem., 2013, 5111-5116 (2013). DOI: 10.1002/ejoc.201300405
 
Identification of cellular proteins interacting with octaarginine (R8) cell-penetrating peptide by photo-crosslinking
Y. Kawaguchi, G. Tanaka, I. Nakase, M. Imanishi, J. Chiba, Y. Hatanaka, S. Futaki
Bioorg. Med. Chem. Lett., 23, 3738-3740 (2013). DOI: 10.1016/j.bmcl.2013.05.008
 
Photoaffinity casting of a coumarine flag for rapid identification of ligand-binding sites within protein
S. Morimoto, T. Tomohiro, N. Maruyama, Y. Hatanaka
Chem. Commun., 49, 1811-1813 (2013). DOI: 10.1039/C3CC38594A
 
Synthesis of photoreactive 2-phenethylamine derivatives - Synthesis of adenosine derivatives enabling functional analysis of adenosine receptors by photoaffinity labeling
Y. Murai, K. Masuda, Y. Ogasawara, L. Wang, Y. Hashidoko, Y. Hatanaka, S. Iwata, T. Kobayashi, M. Hashimoto
Eur. J. Org. Chem., 2013, 2428-2433 (2013). DOI: 10.1002/ejoc.201201657
 
A supramolecular DNA self-assembly based on beta-cyclodextrin-adamantane complexation as a bioorthogonal sticky end motif
J. Chiba, A. Sakai, S. Yamada, K. Fujimoto, M. Inouye
Chem. Commun., 49, 6454-6456 (2013). DOI: 10.1039/C3CC43109F
 
Syntheses and electrochemical properties of novel aminopyrimidinone derivatives as a new class of abasic-site binders
J. Chiba, Y. Doi, M. Inouye
Res. Chem. Intermed., 39, 177-183 (2013). DOI: 10.1007/s11164-012-0641-7
 
 
2012
 
Chemo-enzymatic synthesis of 1'-photoreactive sucrose derivatives via ether linkage
Y. Tsunekawa, K. Masuda, M. Muto, Y. Murai, Y. Hashidoko, Y. Orikasa, Y. Oda, Y. Hatanaka, M. Hashimoto
Heterocycles, 84, 283-290 (2012). DOI: 10.3987/COM-11-S(P)19
 
Comprehensive synthesis of photoreactive (3-trifluoromethyl)diazirinyl indole derivatives from 5- and 6-trifluoroacetylindoles for photoaffinity labeling
Y. Murai, K. Masuda, Y. Sakihama, Y. Hashidoko, Y. Hatanaka, M. Hashimoto
J. Org. Chem., 77, 8581-8587 (2012). DOI: 10.1021/jo301552m
 
CXCR4 stimulates macropinocytosis: Implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV
G. Tanaka, I. Nakase, Y. Fukuda, R. Masuda, S. Oishi, K. Shimura, Y. Kawaguchi, T. Takatani-Nakase, U. Langel, A. Graslund, K. Okawa, M. Matsuoka, N. Fujii, Y. Hatanaka, S. Futaki
Chem. Biol., 19, 1437-1446 (2012). DOI: 10.1016/j.chembiol.2012.09.011
 
Electrochemical direct detection of DNA deamination catalyzed by APOBEC3G
J. Chiba, T. Kouno, S. Aoki, H. Sato, J.Y. Zhang, H. Matsuo, M. Inouye
Chem. Commun., 48, 12115-12117 (2012). DOI: 10.1039/C2CC36779C
 
Furanose ring conformations in a 1'-alkynyl C-nucleoside and the dinucleotide 
J. Chiba, W. Shirato, Y. Yamade, B.-S. Kim, S. Matsumoto, M. Inouye
Tetrahedron, 68, 9045-9049 (2012). DOI: 10.1016/j.tet.2012.08.057
 
 
2011
 
Photochemical construction of coumarin fluorophore on affinity-anchored protein
T. Tomohiro, K. Kato, S. Masuda, H. Kishi, Y. Hatanaka
Bioconjugate Chem., 22, 315-318 (2011). DOI: 10.1021/bc100598r
 
Rapidly photoactivatable ATP probes for specific labeling of tropomyosin within the actomyosin protein complex
S. Masuda, T. Tomohiro, Y. Hatanaka
Bioorg. Med. Chem. Lett., 21, 2252-2254 (2011). DOI: 10.1016/j.bmcl.2011.02.113
 
Hexamethyldisilazane-promoted Sonogashira reaction of polyfunctionalized N-containing heterocycles
M. Inouye, Y. Doi, J. Azuchi, W. Shirato, J. Chiba, H. Abe
Heterocycles, 82, 1137-1141 (2011). DOI: 10.3987/COM-10-S(E)89
 
 
2010
 
Efficient approach for profiling photoaffinity labeled peptides with a cleavable biotinyl photoprobe
N. B. Bongo, T. Tomohiro, Y. Hatanaka
Bioorg. Med. Chem. Lett., 20, 1834-1836 (2010). DOI: 10.1016/j.bmcl.2010.01.164
 
Identification of a substrate-binding site in a peroxisomal beta-oxidation enzyme by photoaffinity labeling with a novel palmitoyl derivative
Y. Kashiwayama, T. Tomohiro, K. Narita, M. Suzumura, T. Glumoff, J. K. Hiltunen, P. P. van Veldhoven, Y. Hatanaka, T. Imanaka
J. Biol. Chem., 285, 26315-26325 (2010). DOI: 10.1074/jbc.M110.104547
 
Photoactive ligands probing the sweet taste receptor. Design and synthesis of highly potent diazirinyl D-phenylalanine derivatives
K. Masuda, A. Koizumi, T. Misaka, Y. Hatanaka, K. Abe, T. Tanaka, M. Ishiguro, M. Hashimoto
Bioorg. Med. Chem. Lett., 20, 1081-1083 (2010). DOI: 10.1016/j.bmcl.2009.12.029
 
Simple deuterium introduction at alpha-position of carbonyl in diazirinyl derivatives for photoaffinity labeling
Y. Murai, M. Takahashi, Y. Muto, Y. Hatanaka, M. Hashimoto
Heterocycles, 82, 909-915 (2010). DOI: 10.3987/COM-10-S(E)57
 
Synthesis and properties of diazirinyl organo-platinum compounds for manipulations of photoaffinity labeled components
 M. Hashimoto, K. Furukawa, T. Tomohiro, Y. Hatanaka
Chem. Pharm. Bull., 58, 405-407 (2010). DOI: 10.1248/cpb.58.405
 
Electrochemical detection of insertion/deletion mutations based on enhanced flexibility of bulge-containing duplexes on electrodes
J. Chiba, A. Akaishi, R. Ikeda, M. Inouye
Chem. Commun., 46, 7563-7565 (2010). DOI: 10.1039/C0CC02371J
 
Specific induced circular dichroism and enhanced B to Z transitions of duplexes stabilized by chromophore-linked alkynylnucleoside residues
K. Fujimoto, S. Aizawa, I. Oota, J. Chiba, M. Inouye
Chem. Eur. J., 16, 2401-2406 (2010). DOI: 10.1002/chem.200902882

総説・解説 Reviews and Accounts

 
Development and leading-edge application of innovative photoaffinity labeling
Y. Hatanaka
Chem. Pharm. Bull., 63, 1-12 (2015). DOI: 10.1248/cpb.c14-00645

Diazirine-based multifunctional photo-probes for affinity-based elucidation of protein-ligand interaction
T. Tomohiro, Y. Hatanaka
Heterocycles, 89, 2697-2727 (2014). DOI: 10.3987/REV-14-803

「遺伝子の違いをDNAの柔軟性で見分ける」
千葉順哉、井上将彦
ファルマシア, 50, No.11, 1096-1100 (2014).
 
「巨大分子をゲストとするナノカプセルのテーラー・メイドを目指して」
千葉順哉、畑中保丸
日本ケミカルバイオロジー学会 Chemical Biology, 4, No.1, 10 (2011).
 
Exotic DNA made of nonnatural bases and natural phosphodiester bonds
J. Chiba, M. Inouye
Chem. Biodivers., 7, 259-282 (2010). DOI: 10.1002/cbdv.200900282

著書・予稿 Books and Proceedings

 
薬の標的を同定し結合部位を解析する光技術
友廣 岳則
光アライアンス, 29(6), 12-16 (2018).
 
アフィニティークロマトグラフィー
友廣 岳則、畑中 保丸
パートナー分析化学 II (改訂第3版), 173-178 (2017).
 
"Tag-creation approaches for highly efficient profiling of interacting proteins and domains"
T. Tomohiro
In Photoaffinity Labeling for Structural Probing within Protein, Y. Hatanaka, M. Hashimoto, Eds
Springer International Publishing, 2017, pp 13-43.  eBook Site
 
"Design and preparation of a compact multifunctional diazirine-based photocross-linker"
S. Yasui, S. Morimoto, J. Chiba, Y. Hatanaka, T. Tomohiro
Photomed. Photobiol., 38, 7-8 (2016).
 
"Methanesulfonyl azide (1st update)"
J. Chiba, T. Tomohiro, Y. Hatanaka
In e-EROS Encyclopedia of Reagents for Organic Synthesis, D. Crich, Ed
WILEY, 2015, RM069.pub2.

特許 Patents

「2-デオキシ-2,3-ジデヒドロシアル酸誘導体およびその製造法」
畑中 保丸、千葉 順哉、友廣 岳則、中山 純
特許第6453050号(2018年12月21日)
 
「チオアミド誘導体」
千葉 順哉、畑中 保丸、友廣 岳則
特許第6440250号(2018年11月30日)
 
「蛍光性質量標識プローブ」
友廣 岳則、畑中 保丸
特許第6145742号(2017年5月26日)
 
「スルホニルアジド誘導体およびアシルスルホンアミド誘導体の製造方法並びにそれらの利用」
畑中 保丸、千葉 順哉、友廣 岳則
特許第6112659号(2017年3月24日)