Alkam, T.,
Nitta, A., Mizoguchi, H., Saito, K., Seshima, M., Itoh, A., Yamada, K. and
Nabeshima, T.: Restraining tumor necrosis factor-alpha by thalidomide prevents
the Abeta-induced impairment of recognition memory in mice. Behav. Brain Res., 189, 100-106
(2008)
Niwa, M., Nitta, A., Cen, X.,
Kitaichi, K., Ozaki, N., Yamada, K. and Nabeshima, T.: A novel molecule ‘shati’ increases dopamine uptake via the induction of
tumor necrosis factor-α in pheochromocytoma-12
cells. J. Neurochem., 107, 1697-1708 (2008)
Kawanokuchi, J., Shimizu, K.,
Nitta, A., Yamada, K., Mizuno, T., Takeuchi, H. and Suzumura, A.: Production and functions of IL-17 in
microglia. J.
Neuroimmunol., 194, 54-61 (2008)
Alkam, T., Nitta, A., Mizoguchi, H., Itoh, A., Murai, R., Nagai, T.,
Yamada, K. and Nabeshima, T.: The
extensive nitration of neurofilament light chain in the hippocampus is
associated with the cognitive impairment induced by amyloid β in mice. J. Pharmacol.
Exp. Ther., 327, 137-147 (2008)
Cen, X., Nitta, A., Ibi,
D., Zhao, Y., Niwa, M., Taguchi, K., Hamada,
M., Ito, Y., Ito, Y., Wang, L. and Nabeshima, T.: Identification
of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization.
Mol. Psychiatry, 13, 451-463 (2008) (-IMAGE; “Piccolo regulates dopamine
transporter internalization via PIP2”, Mol. Psychiatry,
13, 349, 2008)
Yan, Y., Yamada, K.,
Nitta, A. and Nabeshima, T.: Transient drug-primed but persistent cue-induced
reinstatement of extinguished methamphetamine-seeking behavior in mice. Behav.
Brain Res., 177, 261-268 (2007)
Niwa, M., Nitta, A., Shen, L., Noda, Y. and Nabeshima, T.: Involvement of
glial cell-line derived neurotrophic factor inhibitory effects of a
hydorophobic dipeptide Leu-Ile on morphine-induced sensitization and rewarding
effects. Behav. Brain Res., 179, 167-171 (2007)
Alkam, T.,
Nitta, A., Mizoguchi, H., Itoh, A. and Nabeshima, T.: A natural scavenger of
peroxynitrites, rosmarinic acid, protects against impairment of memory induced
by Aβ25-35. Behav. Brain Res., 180, 139-145
(2007)
Murai, R., Noda, Y., Matsui,
K., Kamei, H., Mouri, A., Matsuba, K., Nitta, A., Furukawa, H. and Nabeshima,
T.: Hypofunctional glutamatergic neurotransmission in the prefrontal cortex is
involved in the emotional deficit induced by repeated treatment with
phencyclidine in mice: implications for abnormalities of glutamate release and
NMDA-CaMKU signaling. Behav. Brain Res.,
180, 152-160 (2007)
Niwa, M.,
Nitta, A., Yamada, Y., Nakajima, A., Saito, K., Seishima, M., Shen, L., Noda,
Y., Furukawa, S. and Nabeshima, T.: An inducer for glial cell line-derived
neurotrophic factor and tumor necrosis factor-α protects against
methamphetamine-induced rewarding effects and sensitization. Biol. Psychiatry, 61, 890-901 (2007)
Niwa, M., Nitta, A., Yamada, Y.,
Nakajima, A., Saito, K., Seishima, M., Noda, Y. and Nabeshima, T.: Tumor necrosis factor-α and its inducer inhibit morphine-induced rewarding effects and sensitization. Biol. Psychiatry, 62, 658-668 (2007)
Yan, Y., Yamada, K., Niwa, M., Nagai, T.,
Nitta, A. and Nabeshima, T.: Enduring vulnerability
to reinstatement of methamphetamine-seeking behavior in glial cell line-derived
neurotrophic factor mutant mice. FASEB
J., 21, 1994-2004 (2007)
Mizoguchi, H., Yamada,
K., Niwa, M., Mouri, A., Mizuno, T., Noda, Y., Nitta, A., Itohara, S., Banno, Y.
and Nabeshima, T.: Reduction of methamphetamine-induced sensitization and
reward in matrix metalloproteinase-2 and -9 deficient mice. J. Neurochem., 100,
1579-1588 (2007)
Mizoguchi, H., Yamada, K., Mouri, A., Niwa,
M., Mizuno, T., Noda, Y., Nitta, A. Itohara, S., Banno, Y. and Nabeshima, T.:
Role of matrix metalloproteinase and tissue inhibitor of MMP in
methamohetamine-induced behavioral sensitization and Reward: implications for
dopamine reseptor down-regulation and dopamine release. J. Neurochem., 102,
1548-1560 (2007)
Niwa, M., Nitta, A., Mizoguchi, H., Ito, Y., Noda, Y., Nagai, T. and
Nabeshima, T.: A novel molecule ‘shati’ is involved in methamphetamine-induced
hyperlocomotion, sensitization, and conditioned place preference. J. Neurosci., 27, 7604-7615 (2007)
Amioka, K., Kuzuya, T., Kushihara, H., Ejiri,
M., Nitta, A. and Nabeshima, T.: Carvedilol increases ciclosporin
bioavailability by inhibiting P-glycoprotein-mediated transport. J. Pharm.
Pharmacol., 59, 1383-1387 (2007)
Wang, D., Noda, Y., Tsunekawa, H., Zhou, Y.,
Miyazaki, M., Senzaki, K., Nitta, A. and Nabeshima, T.: Role of NMDA receptors
in antidepression-like effects of sigma1 receptor agonist SA-4503 in
olfactory bulbectomized rats. J. Pharmacol. Exp. Ther., 322, 1305-1314 (2007)
Mouri, A.,
Noda, Y., Noda, A., Nakamura, T., Tokura, T., Yura, Y., Nitta, A., Furukawa, H.
and Nabeshima, T.: Involvement of a dysfunctional dopamine-D1/NMDA-NR1 and CaMKU pathway in the impairment of latent learning in a model of
schizophrenia induced by phencyclidine. Mol. Pharmacol., 71, 1598-1609 (2007)
Wang, D., Noda, Y., Zhou, Y., Nitta, A.,
Furukawa, H. and Nabeshima, T.: Synergistic
effect of galantamine with risperidone on impairment of social interaction in
phencyclidine-treated mice as a schizophrenic animal model. Neuropharmacology, 52, 1179-1187 (2007)
Wang, D., Noda, Y., Zhou, Y.,
Nitta, A., Furukawa H. and Nabeshima, T.:
Synergistic effect of combined treatment with risperidone and galantamine on
phencyclidine-induced impairment of latent visuospatial learning and memory:
role of nAChR activation-dependent increase of dopamine D1
receptor-mediated neurotransmission. Neuropharmacology, 53, 379-389 (2007)
Wang, D., Noda, Y., Zhou, Y., Mouri, A., Mizoguchi, H., Nitta, A., Chen,
W. and Nabeshima, T.: The allosteric potentiation of nicotinic
acetylcholine receptors by galantamine ameliorates the cognitive dysfunction in
beta amyloid25-35 i.c.v.-injected mice: involvement of dopaminergic
systems. Neuropsychopharmacology, 32, 1261-1271 (2007)
Yan, Y., Yamada, K., Mizoguchi, H., Noda, Y., Nagai, T., Nitta, A. and Nabeshima,
T.:Reinforcing effects of morphine are reduced in tissue plasminogen activator
(tPA)-knockout mice. Neuroscience, 146, 50-59 (2007)
Yan, Y.,
Nitta, A., Mizoguchi, H., Yamada, K. and Nabeshima, T.: Relapse of methamphetamine-seeking behavior in
C57BL/6J mice demonstrated by a reinstatement procedure involving intravenous
self-adminisiration. Behav. Brain Res., 168, 137-143 (2006)
Yan, Y., Nitta, A., Mizuno,
T., Nakajima, A., Yamada, K. and Nabeshima, T. : Discriminative-stimulus effects of methamphetamine and morphine in rats
are attenuated by cAMP-related compounds.Behav. Brain Res., 173, 39-46 (2006)
Kuno,
R., Yoshida, Y., Nitta, A., Nabeshima, T., Wang, J., Sonobe, Y., Kawanokuchi,
J., Takeuchi, H., Mizuno, T. and Suzumura, A.: The role of TNF-alpha and its
receptors in the production of NGF and GDNF by astrocytes. Brain Res., 1116, 12-18 (2006)
Ishikawa,
K., Nitta, A., Mizoguchi, H., Mohri, A., Murai, R., Miyamoto, Y., Noda, Y.,
Kitaichi, K., Yamada, K. and Nabeshima, T.: Effects of single and repeated
administration of methamphetamine or morphine on neuroglycan C gene expression
in the rat brain. Int. J. Neuropsychopharmacol., 9, 407-415 (2006)
Cen, X., Nitta, A., Ohya, S., Zhao, Y., Ozawa, N., Mouri, A., Ibi, D.,
Wang, L., Suzuki, M., Saito, K., Ito, Y., Kawagoe, T., Noda, Y., Ito, Y., Furukawa,
S. and Nabeshima, T.: An analogue of dipeptide-like structure of
FK506 increases GDNF expression through CREB activated by Hsp90/Akt signaling
pathway. J.
Neurosci., 26, 3335-3344 (2006)
Mizuno, T., Kuno, R., Nitta, A., Nabeshima,
T., Zhang, G., Kawanokuchi, J., Wang, J., Jin, S., Takeuchi, H. and Suzumura,
A.: Protective effects of nicergoline against neuronal cell death induced by
activated microglia and astrocytes. Brain Res., 1066, 78-85 (2005)
Miyoshi, M., Nadai, M., Nitta,
A., Ueyama, J., Shimizu, A., Takagi, K., Nabeshima, T., Takagi, K., Saito, K.
and Hasegawa, T.: Role of tumor necrosis factor-α in down-regulation of hepatic cytochrome P450
and P-glycoprotein by endotoxin. Eur. J. Pharmacol., 507, 229-237 (2005)
Hashimoto, M., Nitta, A.,
Fukumitsu, H., Nomoto, H., Shen, L. and Furukawa, S.: Involvement of glial cell
line-derived neurotrophic factor in activation processes of rodent macrophages.
J. Neurosci. Res., 79, 476-487 (2005)
Enomoto, T., Noda, Y., Mouri, A., Shin, E.J., Wang, D.,
Murai, R., Hotta, K., Furukawa, H., Nitta, A., Kim, H.C. and Nabeshima, T.:
Long-lasting impairment of associative learning is correlatied with dysfunction
of N-methyl-D-aspartate-Extracellular signaling-regulated kinase signaling in mice after withdrawal from repeated
administration of phencyclidine. Mol. Pharmacol., 68, 1765-1774 (2005)
Hashimoto, M., Nitta, A., Fukumitsu,
H., Nomoto, H., Shen, L. and Furukawa, S.: Inflammation-induced GDNF improves
locomotor function after spinal cord injury. Neuroreport, 16, 99-102 (2005)
Nakashima, S., Matsuyama, Y., Nitta, A.,
Sakai, Y. and Ishiguro, N.: Highly efficient transfection of human marrow
stromal cells by nucleofection. Transplant. Proc., 37, 2290-2292 (2005)
Hamdy, M.M., Noda, Y.,
Miyazaki, M., Mamiya, T., Nozaki, A., Nitta, A., Sayed, M., Assi, A.A., Gomaa,
A. and Nabeshima, T.: Molecular mechanisms in dizocilpine-induced attenuation
of development of morphine dependence: an association with cortical
Ca2+/calmodurin-dependent signal cascade. Behav. Brain Res., 152, 263-270
(2004)
Wang, D., Noda, Y., Zhou, Y.,
Nitta, A., Nabeshima, T. and Yu, Q.: Effects of sodium houttuyfonate on
phosphorylation of CaMKII, CREB and ERK 1/2 and expression of c-Fos in
macrophages. Int. Immunopharmacol., 4, 1083-1088 (2004)
Nakajima, A., Yamada, K., He,
J., Zeng, N., Nitta, A. and Nabeshima, T.: Anatomical substrates for the
discriminative stimulus effects of methamphetamine in rats. J. Neurochem., 91, 308-317 (2004)
Nakajima, A., Yamada, K.,
Nagai, T., Uchiyama, T., Miyamoto, Y., Mamiya, T., He, J., Nitta, A., Mizuno,
M., Tran, M. H., Seto, A., Yoshimura, M., Kitaichi, K., Hasegawa, T., Saito,
K., Yamada, Y., Seishima, M., Sekikawa, K., Kim, H.C. and Nabeshima, T.: Role
of tumor necrosis factor-α in methamphetamine-induced drug dependence and
neurotoxicity. J. Neurosci., 24, 2212-2225 (2004)
Nitta, A., Zheng, W.H. and
Quirion, R.: Insulin-like growth factor-1 prevents neuronal cell death induced
by corticosterone through the activation of the PI3K/Akt pathway. J. Neurosci. Res.,
76, 98-103 (2004)
Kinukawa,
H., Jikou, T., Nitta, A., Furukawa, Y., Hashimoto, M., Fukumitsu, H., Nomoto, H.
and Furukawa, S.: Cyclic AMP/protein Kinase A
signal attenuates Ca2+-induced fibroblast growth factor-1 synthesis in rat
cortical neurons. J. Neurosci. Res., 77, 487-497 (2004)
Nitta, A.,
Nishioka, H., Fukumitsu, H., Furukawa, Y., Sugiura, H., Shen, L. and Furukawa,
S.: Hydrophobic dipeptide, Leu-Ile, protects against neuronal death by inducing
brain-derived neurotrophic factor and glial cell line-derived neurotrophic
synthesis. J. Neurosci. Res., 78, 250-258 (2004)
Mizoguchi, H., Yamada, K.,
Mizuno, M., Mizuno, T., Nitta, A., Noda, Y. and Nabeshima, T.: Regulations of
methamphetamine reward by extracellular signal-regulated kinase 1/2/ets-like
gene-1 signaling pathway via the activation of dopamine receptors. Mol.
Pharmacol., 65, 1293-1301 (2004)
Maruyama, W., Nitta, A.,
Shamoto-Nagai, M., Hirata, Y., Akao, Y., Yodim, M., Furukawa, S., Nabeshima, T.
and Naoi, M.: N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell
line-derived neurotrophic factor(GDNF) in neuroblastoma SH-SY5Y cells through
activation of NF-κB transcription factor. Neurochem. Int., 44, 393-400 (2004)
Yamada, Y.,
Shimizu, K., Nitta, A., Soumiya, H., Fukumitsu, H. and Furukawa, S.: Axonal regrowth
downregulates the synthesis of glial cell line-derived neurotrophic factor in
the lesioned rat sciatic nerve. Neurosci. Lett., 364, 11-15 (2004)
Nagai, T., Yamada, K.,
Yoshimura, M., Ishikawa, K., Miyamoto, Y., Hashimoto, K., Noda, Y., Nitta, A.
and Nabeshima T.: The tissue plasminogen activator-plasmin system participates
in the rewarding effect of morphine by regulating dopamine release. Proc. Natl.
Acad. Sci. USA., 101, 3650-3655 (2004)
Kim, H.C., Yamada, K., Nitta,
A., Olariu, A., Tran, M. H., Mizuno, M., Nakajima, A., Nagai, T., Kamei, H.,
Jhoo, W.K., Im, D.H., Shin, E.J., Hjelle, O.P., Ottersen, O.P., Park, S.C.,
Kato, K., Mirault, M.E. and Nabeshima, T.: Immunocytochemical evidence that
amyloid β(1-42) impairs endogenous antioxidant systems in vivo. Neuroscience,
119, 399-419 (2003)
O’Donnell, J., Stemmelin, J.,
Nitta, A., Brouillette, J. and Quirion, R.: Gene expression profiling following
chronic NMDA receptor blockade-induced learning deficits in rats. Synapse, 50,
171-180 (2003)
Miyake, K., Yamamoto, W.,
Tadokoro, M., Takagi, N., Sasakawa, K., Nitta, A., Furukawa, S. and Takeo, S.: Alterations
in hippocampal GAP-43, BDNF, and L1 following sustained cerebral ischemia. Brain
Res., 935, 24-31 (2002)
Murakami, Y., Furukawa, S.,
Nitta, A. and Furukawa, Y.: Accumulation of nerve growth factor protein at both
rostral and caudal stumps in the transected rat spinal cord. J. Neurol. Sci.,
198, 63-69 (2002)
Sometani, A., Nitta, A., Nomoto,
H., Furukawa, Y. and Furukawa, S.: 4-Methylcatechol stimulates phosphorylation
of Trk family neurotrophin receptors and MAP kinases in cultured rat cortical
neurons. J. Neurosci. Res., 70, 335-339 (2002)
Ohmiya, M., Shudai, T., Nitta,
A., Nomoto, H., Furukawa, Y. and Furukawa, S.: Brain-derived neurotrophic
factor alters cell migration of particular progenitors in the developing mouse
cerebral cortex. Neurosci. Lett., 317, 21-24 (2002)
Fukuta,
T., Nitta, A., Itoh, A., Furukawa, S. and Nabeshima, T.: Difference in toxicity
of β-amyloid peptide with aging in relation to nerve growth factor
content in rat brain. J. Neural Transm., 108, 221-230 (2001)
Ohmiya, M., Fukumitsu, H.,
Nitta, A., Nomoto, H. and Furukawa, Y.: Administration of FGF-2 to embryonic
mouse brain induces hydrocephalic brain morphology and aberrant differentiation
of neurons in the postnatal cerebral cortex. J. Neurosci. Res., 65, 228-235
(2001)
Sometani, A., Kataoka, H.,
Nitta, A., Fukumitsu, H., Nomoto, H. and Furukawa, S.: Transforming growth
factor-β1 enhances expression of brain-derived neurotrophic factor and its
receptor, TrkB, in neurons cultured from rat cerebral cortex. J. Neurosci. Res.,
66, 369-376 (2001)
Fukumitsu, H., Ohmiya, M.,
Nitta, A., Furukawa, S., Mima, T. and Mori, K.: Aberrant expression of
neurotrophic factors in the ventricular progenitor cells of infant congenitally
hydrocephalic NTX rats. Childs Nerv. Syst., 16, 516-521 (2000)
Kawakami, H., Nitta, A.,
Matsuyama, Y., Kamiya, M., Satake, K., Sato, K., Kondou, K., Iwata, H. and Furukawa,
S.: Increase in neurotrophin-3 expression followed by Purkinje cell
degeneration in the adult rat cerebellum after spinal cord transection. J.
Neurosci. Res., 62, 668-674 (2000)
Ikemoto, A., Nitta, A.,
Furukawa, S., Ohnishi, M., Nakamura, A., Fujii, Y. and Okuyama, H.: Dietary n-3
fatty acid deficiency decreases nerve growth factor content in rat hippocampus.
Neurosci. Lett., 285, 99-102 (2000)
Furukawa, S., Nitta, A. and
Furukawa, Y.: Stimulation of neurotrophin synthesis by 4-methycatechol: a
promosing approach to the treatment of neurodegeneration. Biomedical Reviews, 10, 45-54 (1999)
Itoh, A., Akaike, T., Sokabe,
M., Nitta, A., Iida, R., Olariu, A., Yamada, K. and Nabeshima, T.: Impairments
of long-term potentiation in hippocampal slices of β-amyloid-infused
rats. Eur. J. Pharmacol., 382, 167-175 (1999)
Mizuma, H., Takagi, K., Miyake,
K., Takagi, N., Ishida, K., Takeo, S., Nitta, A., Nomoto, H., Furukawa, Y. and
Furukawa, S.: Microsphere embolism-induced elevation of nerve growth factor
level and appearance of nerve growth factor immunoreactivity in activated
T-lymphocytes in the rat brain. J. Neurosci. Res., 55, 749-761 (1999)
Nitta, A., Ohmiya, M., Sometani,
A., Itoh, M., Nomoto, H., Furukawa, Y. and Furukawa, S.: Brain-derived
neurotrophic factor prevents neuronal cell death induced by corticosterone. J.
Neurosci. Res., 57, 227-235 (1999)
Nitta, A., Ito M., Fukumitsu, H.,
Ohmiya, M., Ito, H., Sometani, A., Nomoto, H., Furukawa, Y. and Furukawa, S.: 4-methylcatechol
increases brain-derived neurotrophic factor content and mRNA expression in
cultured brain cells and in the brain in vivo. J. Pharmcol. Exp. Ther., 291,
1276-1283 (1999)
Nitta, A., Ohmiya, M.,
Jin-nouchi, T., Sometani, A., Asami, T., Fukumitsu, H., Nomoto, H. and Furukawa,
S.: Endogenous neurotrophin-3 is retrogradely transported in the rat sciatic
nerve. Neuroscience, 88, 679-685 (1999)
Fukumitsu, H., Ohmiya, M.,
Sometani, A., Nitta, A., Nomoto, H., Furukawa, Y. and Furukawa, S.: Induction
of a physiologically active brain-derived neurotrophic factor in the infant rat
brain by peripheral administration of 4-methylcatechol. Neurosci. Lett., 274,
115-118 (1999)
Ghelardini, C., Galeotti, N.,
Bartolini, A., Furukawa, S., Nitta, A., Manetti, D. and Gualtieri, F.: Memory
facilitation and stimulation of endogenous nerve growth factor synthesis by the
acetylcholine releaser PG-9. Jpn. J. Pharmacol., 78, 245-251 (1998)
Furukawa, S., Sugihara, Y.,
Iwasaki, F., Fukumitsu, H., Nitta, A., Nomoto, H. and Furukawa, Y.: Brain-derived
neurotrophic factor-like immunoreactively in the adult rat central nervous
system predominantly distributed in neurons with substantial amounts of
brain-derived neurotrophic factor messenger RNA or responsiveness to
brain-derived neurotrophic factor. Neuroscience, 82, 653-670 (1998)
Fukumitsu, H., Furukawa, Y.,
Tsusaka, M., Kinukawa, H., Nitta, A., Nomoto, H., Mima, T. and Furukawa, S.: Simultaneous
expression of brain-derived neurotrophic factor and neurotrophin-3 in
cajal-retzius, subplate and ventricular progenitor cells during early
development stages of the rat cerebral cortex. Neuroscience, 84, 115-127 (1998)
Itoh, A., Nitta, A., Hirose,
M., Hasegawa, T. and Nabeshima, T.: Effects of metrifonate on impairment of
learning and dysfunction of cholinergic neuronal system in basal
forebrain-lesioned rats. Behav. Brain Res., 83, 165-167 (1997)
Nitta, A., Ogihara, Y., Onishi,
J., Hasegawa, T., Furukawa, S. and Nabeshima, T.: Oral administration of
propentofylline, a stimulator of nerve growth factor (NGF) synthesis, recovers
cholinergic neuronal dysfunction induced by the infusion of anti-NGF antibody
into the rat septum. Behav. Brain Res., 83, 201-204 (1997)
Itoh, A., Nitta, A., Katono,
Y., Usui, M., Naruhashi, K., Iida, R., Hasegawa, T. and Nabeshima, T.: Effects
of metrifonate on memory impairment and cholinergic dysfunction in rats. Eur.
J. Pharmacol., 322, 11-19 (1997)
Nitta, A., Fukuta, T.,
Hasegawa, T. and Nabeshima, T.: Continuous infusion of β-amyloid
protein into the rat cerebral ventricle induces learning impairment and
neuronal and morphological degeneration. Jpn. J. Pharmacol., 73, 51-57 (1997)
Nitta, A., Fukumitsu, H.,
Kataoka, H., Nomoto, H. and Furukawa, S.: Administration of corticosterone alters
intracellular localization of brain-derived neurotrophic factor-like
immunoreactivity in the rat brain. Neurosci. Lett., 226, 115-118 (1997)
Fukumitsu, H., Ohashi, A.,
Nitta, A., Nomoto, H. and Furukawa, S.: BDNF and NT-3 modulate expression and
threonine phospherylation of microtubule-associated protein 2 analogues, and
alter their distribution in the developing rat cerebral cortex. Neurosci. Lett.,
238, 107-110 (1997)
Nitta, A., Naruhashi, K.,
Umemura, M., Hasegawa, T., Furukawa, H., Sekiguchi, F., Ishibashi, K. and
Nabeshima, T.: Age-related changes in learning and memory and cholinergic
neuronal function in senescence accelerated mice (SAM). Behav. Brain Res., 72,
49-55 (1996)
Nitta, A., Ogihara, Y., Onishi,
J., Hasegawa, T., Furukawa, S. and Nabeshima, T.: Propentofylline prevents
neuronal dysfunction induced by infusion of anti-nerve growth factor antibody
into the rat septum. Eur. J. Pharmacol., 307, 1-6 (1996)
Itoh, A., Nitta, A., Nadai, M.,
Nishimura, K., Hirose, M., Hasegawa, T. and Nabeshima, T.: Dysfunction of
cholinergic and dopaminergic neuronal systems in β-amyloid protein-infused rats. J. Neurochem.,
66, 1113-1117 (1996)
Yamada, K., Nitta, A., Saito,
T., Hu, J. and Nabeshima, T.: Changes in ciliary neurotrophic factor content in
the rat brain after continuous intracerebroventricular infusion of β-amyloid
(1-40) protein. Neurosci. Lett., 201, 155-158 (1995)
Nitta, A., Furukawa, Y.,
Hayashi, K., Hasegawa, T. and Nabeshima, T.: Nerve growth factor content of rat
brain increases following basal-forebrain lesions induced by ibotenic acid but
not by electrolysis. Biol. Pharm. Bull., 17, 34-38 (1994)
Nabeshima, T., Nitta, A., Fuji,
K., Kameyama, T. and Hasegawa, T.: Oral administration of NGF synthesis
stimulators recovers reduced brain NGF content in aged rats and cognitive
dysfunction in basal-forebrain-lesioned rats. Gerontology, 40 (Suppl. 2), 46-56
(1994)
Nabeshima, T., Itoh, A.,
Kobayashi, K., Morita, S., Mizuguchi, T., Sawada, H., Nitta, A., Hasegawa, T.,
Hayashi, K. and Nagatsu, T.: Effects of subacute administration of
methamphetamine and nicotine on locomotor activity in transgenic mice
expressing the human tyrosine hydroxylase gene. J. Neural Transm. (Gen. Sect.),
97, 41-49 (1994)
Nitta, A., Murakami, Y.,
Furukawa, Y., Kawatsura, W., Hayashi, K., Yamada, K., Hasegawa, T. and
Nabeshima, T.: Oral administration of idebenone induces nerve growth factor in
the brain and improves learning and memory in basal forebrain-lesioned rats.
Naunyn Schmiedebergs Arch. Pharmacol., 349, 401-407 (1994)
Nitta, A., Itoh, A., Hasegawa,
T. and Nabeshima, T.: β-Amyloid protein-induced Alzheimer’s disease animal model. Neurosci.
Lett., 170, 63-66 (1994)
Nitta, A., Katono, Y., Itoh,
A., Hasegawa, T. and Nabeshima, T.: Nicotine reverses scopolamine-induced
impairment of performance in passive avoidance task in rats through its action
on the dopaminergic neuronal system. Pharmacol. Biochem, Behav., 49, 807-812
(1994)
Nabeshima, T. and Nitta, A.:
Memory impairment and neuronal dysfunction induced by β-amyloid
protein in rats. Tohoku J. Exp. Med., 174, 241-249 (1994)
Nitta, A., Murase, K.,
Furukawa, Y., Hayashi, K., Hasegawa, T. and Nabeshima, T.: Effects of oral
administration of a stimulator for nerve growth factor synthesis in basal
forebrain-lesioned rats. Eur. J. Pharmacol., 250, 23-30 (1993)
Nitta, A., Hayashi, K.,
Hasegawa, T. and Nabeshima, T.: Development of plasticity of brain function
with repeated trainings and passage of time after basal forebrain lesions in
rats. J. Neural Transm. (Gen. Sect.), 93, 37-46 (1993)
Nabeshima, T., Nitta, A. and
Hasegawa, T.: Impairment of learning and memory and the accessory symptom in
aged rat as senile dementia model (3): Oral administration of propentofylline
produces recovery of reduced NGF content in the brain of aged rats. Jpn. J.
Psychopharmacol., 13, 89-95 (1993)
Nitta, A., Murase, K.,
Furukawa, Y., Hayashi, K., Hasegawa, T. and Nabeshima, T.: Memory impairment
and neural dysfunction after continuous infusion of anti-nerve growth factor
antibody into the septum in adult rats. Neuroscience, 57, 495-499 (1993)
Nitta, A., Hasegawa, T. and
Nabeshima, T.: Oral administration of idebenone, a stimulator of NGF synthesis,
recovers reduced NGF content in aged rat brain. Neurosci. Lett., 163, 219-222
(1993)
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