• Alkam, T., Nitta, A., Mizoguchi, H., Saito, K., Seshima, M., Itoh, A., Yamada, K. and Nabeshima, T.: Restraining tumor necrosis factor-alpha by thalidomide prevents the Abeta-induced impairment of recognition memory in mice. Behav. Brain Res., 189, 100-106 (2008)

  • Niwa, M., Nitta, A., Cen, X., Kitaichi, K., Ozaki, N., Yamada, K. and Nabeshima, T.: A novel molecule ‘shati’ increases dopamine uptake via the induction of tumor necrosis factor-α in pheochromocytoma-12 cells. J. Neurochem., 107, 1697-1708 (2008)

  • Kawanokuchi, J., Shimizu, K., Nitta, A., Yamada, K., Mizuno, T., Takeuchi, H. and Suzumura, A.: Production and functions of IL-17 in microglia. J. Neuroimmunol., 194, 54-61 (2008)

  • Alkam, T., Nitta, A., Mizoguchi, H., Itoh, A., Murai, R., Nagai, T., Yamada, K. and Nabeshima, T.: The extensive nitration of neurofilament light chain in the hippocampus is associated with the cognitive impairment induced by amyloid β in mice. J. Pharmacol. Exp. Ther., 327, 137-147 (2008)

  • Cen, X., Nitta, A., Ibi, D., Zhao, Y., Niwa, M., Taguchi, K., Hamada, M., Ito, Y., Ito, Y., Wang, L. and Nabeshima, T.: Identification of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization. Mol. Psychiatry, 13, 451-463 (2008) (-IMAGE; “Piccolo regulates dopamine transporter internalization via PIP2”, Mol. Psychiatry, 13, 349, 2008)

  • Yan, Y., Yamada, K., Nitta, A. and Nabeshima, T.: Transient drug-primed but persistent cue-induced reinstatement of extinguished methamphetamine-seeking behavior in mice. Behav. Brain Res., 177, 261-268 (2007)

  • Niwa, M., Nitta, A., Shen, L., Noda, Y. and Nabeshima, T.: Involvement of glial cell-line derived neurotrophic factor inhibitory effects of a hydorophobic dipeptide Leu-Ile on morphine-induced sensitization and rewarding effects. Behav. Brain Res., 179, 167-171 (2007)

  • Alkam, T., Nitta, A., Mizoguchi, H., Itoh, A. and Nabeshima, T.: A natural scavenger of peroxynitrites, rosmarinic acid, protects against impairment of memory induced by Aβ25-35. Behav. Brain Res., 180, 139-145 (2007)

  • Murai, R., Noda, Y., Matsui, K., Kamei, H., Mouri, A., Matsuba, K., Nitta, A., Furukawa, H. and Nabeshima, T.: Hypofunctional glutamatergic neurotransmission in the prefrontal cortex is involved in the emotional deficit induced by repeated treatment with phencyclidine in mice: implications for abnormalities of glutamate release and NMDA-CaMKU signaling. Behav. Brain Res., 180, 152-160 (2007)

  • Niwa, M., Nitta, A., Yamada, Y., Nakajima, A., Saito, K., Seishima, M., Shen, L., Noda, Y., Furukawa, S. and Nabeshima, T.: An inducer for glial cell line-derived neurotrophic factor and tumor necrosis factor-α protects against methamphetamine-induced rewarding effects and sensitization. Biol. Psychiatry, 61, 890-901 (2007)

  • Niwa, M., Nitta, A., Yamada, Y., Nakajima, A., Saito, K., Seishima, M., Noda, Y. and Nabeshima, T.: Tumor necrosis factor-α and its inducer inhibit morphine-induced rewarding effects and sensitization. Biol. Psychiatry, 62, 658-668 (2007)

  • Yan, Y., Yamada, K., Niwa, M., Nagai, T., Nitta, A. and Nabeshima, T.: Enduring vulnerability to reinstatement of methamphetamine-seeking behavior in glial cell line-derived neurotrophic factor mutant mice. FASEB J., 21, 1994-2004 (2007)

  • Mizoguchi, H., Yamada, K., Niwa, M., Mouri, A., Mizuno, T., Noda, Y., Nitta, A., Itohara, S., Banno, Y. and Nabeshima, T.: Reduction of methamphetamine-induced sensitization and reward in matrix metalloproteinase-2 and -9 deficient mice. J. Neurochem., 100, 1579-1588 (2007)

  • Mizoguchi, H., Yamada, K., Mouri, A., Niwa, M., Mizuno, T., Noda, Y., Nitta, A. Itohara, S., Banno, Y. and Nabeshima, T.: Role of matrix metalloproteinase and tissue inhibitor of MMP in methamohetamine-induced behavioral sensitization and Reward: implications for dopamine reseptor down-regulation and dopamine release. J. Neurochem., 102, 1548-1560 (2007)

  • Niwa, M., Nitta, A., Mizoguchi, H., Ito, Y., Noda, Y., Nagai, T. and Nabeshima, T.: A novel molecule ‘shati’ is involved in methamphetamine-induced hyperlocomotion, sensitization, and conditioned place preference. J. Neurosci., 27, 7604-7615 (2007)

  • Amioka, K., Kuzuya, T., Kushihara, H., Ejiri, M., Nitta, A. and Nabeshima, T.: Carvedilol increases ciclosporin bioavailability by inhibiting P-glycoprotein-mediated transport. J. Pharm. Pharmacol., 59, 1383-1387 (2007)

  • Wang, D., Noda, Y., Tsunekawa, H., Zhou, Y., Miyazaki, M., Senzaki, K., Nitta, A. and Nabeshima, T.: Role of NMDA receptors in antidepression-like effects of sigma1 receptor agonist SA-4503 in olfactory bulbectomized rats. J. Pharmacol. Exp. Ther., 322, 1305-1314 (2007)

  • Mouri, A., Noda, Y., Noda, A., Nakamura, T., Tokura, T., Yura, Y., Nitta, A., Furukawa, H. and Nabeshima, T.: Involvement of a dysfunctional dopamine-D1/NMDA-NR1 and CaMKU pathway in the impairment of latent learning in a model of schizophrenia induced by phencyclidine. Mol. Pharmacol., 71, 1598-1609 (2007)

  • Wang, D., Noda, Y., Zhou, Y., Nitta, A., Furukawa, H. and Nabeshima, T.: Synergistic effect of galantamine with risperidone on impairment of social interaction in phencyclidine-treated mice as a schizophrenic animal model. Neuropharmacology, 52, 1179-1187 (2007)

  • Wang, D., Noda, Y., Zhou, Y., Nitta, A., Furukawa H. and Nabeshima, T.: Synergistic effect of combined treatment with risperidone and galantamine on phencyclidine-induced impairment of latent visuospatial learning and memory: role of nAChR activation-dependent increase of dopamine D1 receptor-mediated neurotransmission. Neuropharmacology, 53, 379-389 (2007)

  • Wang, D., Noda, Y., Zhou, Y., Mouri, A., Mizoguchi, H., Nitta, A., Chen, W. and Nabeshima, T.: The allosteric potentiation of nicotinic acetylcholine receptors by galantamine ameliorates the cognitive dysfunction in beta amyloid25-35 i.c.v.-injected mice: involvement of dopaminergic systems. Neuropsychopharmacology, 32, 1261-1271 (2007)

  • Yan, Y., Yamada, K., Mizoguchi, H., Noda, Y., Nagai, T., Nitta, A. and Nabeshima, T.:Reinforcing effects of morphine are reduced in tissue plasminogen activator (tPA)-knockout mice. Neuroscience, 146, 50-59 (2007)

  • Yan, Y., Nitta, A., Mizoguchi, H., Yamada, K. and Nabeshima, T.: Relapse of methamphetamine-seeking behavior in C57BL/6J mice demonstrated by a reinstatement procedure involving intravenous self-adminisiration. Behav. Brain Res., 168, 137-143 (2006)

  • Yan, Y., Nitta, A., Mizuno, T., Nakajima, A., Yamada, K. and Nabeshima, T. : Discriminative-stimulus effects of methamphetamine and morphine in rats are attenuated by cAMP-related compounds.Behav. Brain Res., 173, 39-46 (2006)

  • Kuno, R., Yoshida, Y., Nitta, A., Nabeshima, T., Wang, J., Sonobe, Y., Kawanokuchi, J., Takeuchi, H., Mizuno, T. and Suzumura, A.: The role of TNF-alpha and its receptors in the production of NGF and GDNF by astrocytes. Brain Res., 1116, 12-18 (2006)

  • Ishikawa, K., Nitta, A., Mizoguchi, H., Mohri, A., Murai, R., Miyamoto, Y., Noda, Y., Kitaichi, K., Yamada, K. and Nabeshima, T.: Effects of single and repeated administration of methamphetamine or morphine on neuroglycan C gene expression in the rat brain. Int. J. Neuropsychopharmacol., 9, 407-415 (2006)

  • Cen, X., Nitta, A., Ohya, S., Zhao, Y., Ozawa, N., Mouri, A., Ibi, D., Wang, L., Suzuki, M., Saito, K., Ito, Y., Kawagoe, T., Noda, Y., Ito, Y., Furukawa, S. and Nabeshima, T.: An analogue of dipeptide-like structure of FK506 increases GDNF expression through CREB activated by Hsp90/Akt signaling pathway. J. Neurosci., 26, 3335-3344 (2006)

  • Mizuno, T., Kuno, R., Nitta, A., Nabeshima, T., Zhang, G., Kawanokuchi, J., Wang, J., Jin, S., Takeuchi, H. and Suzumura, A.: Protective effects of nicergoline against neuronal cell death induced by activated microglia and astrocytes. Brain Res., 1066, 78-85 (2005)

  • Miyoshi, M., Nadai, M., Nitta, A., Ueyama, J., Shimizu, A., Takagi, K., Nabeshima, T., Takagi, K., Saito, K. and Hasegawa, T.: Role of tumor necrosis factor-α in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin. Eur. J. Pharmacol., 507, 229-237 (2005)

  • Hashimoto, M., Nitta, A., Fukumitsu, H., Nomoto, H., Shen, L. and Furukawa, S.: Involvement of glial cell line-derived neurotrophic factor in activation processes of rodent macrophages. J. Neurosci. Res., 79, 476-487 (2005)

  • Enomoto, T., Noda, Y., Mouri, A., Shin, E.J., Wang, D., Murai, R., Hotta, K., Furukawa, H., Nitta, A., Kim, H.C. and Nabeshima, T.: Long-lasting impairment of associative learning is correlatied with dysfunction of N-methyl-D-aspartate-Extracellular signaling-regulated kinase signaling in mice after withdrawal from repeated administration of phencyclidine. Mol. Pharmacol., 68, 1765-1774 (2005)

  • Hashimoto, M., Nitta, A., Fukumitsu, H., Nomoto, H., Shen, L. and Furukawa, S.: Inflammation-induced GDNF improves locomotor function after spinal cord injury. Neuroreport, 16, 99-102 (2005)

  • Nakashima, S., Matsuyama, Y., Nitta, A., Sakai, Y. and Ishiguro, N.: Highly efficient transfection of human marrow stromal cells by nucleofection. Transplant. Proc., 37, 2290-2292 (2005)

  • Hamdy, M.M., Noda, Y., Miyazaki, M., Mamiya, T., Nozaki, A., Nitta, A., Sayed, M., Assi, A.A., Gomaa, A. and Nabeshima, T.: Molecular mechanisms in dizocilpine-induced attenuation of development of morphine dependence: an association with cortical Ca2+/calmodurin-dependent signal cascade. Behav. Brain Res., 152, 263-270 (2004)

  • Wang, D., Noda, Y., Zhou, Y., Nitta, A., Nabeshima, T. and Yu, Q.: Effects of sodium houttuyfonate on phosphorylation of CaMKII, CREB and ERK 1/2 and expression of c-Fos in macrophages. Int. Immunopharmacol., 4, 1083-1088 (2004)

  • Nakajima, A., Yamada, K., He, J., Zeng, N., Nitta, A. and Nabeshima, T.: Anatomical substrates for the discriminative stimulus effects of methamphetamine in rats.  J. Neurochem., 91, 308-317 (2004)

  • Nakajima, A., Yamada, K., Nagai, T., Uchiyama, T., Miyamoto, Y., Mamiya, T., He, J., Nitta, A., Mizuno, M., Tran, M. H., Seto, A., Yoshimura, M., Kitaichi, K., Hasegawa, T., Saito, K., Yamada, Y., Seishima, M., Sekikawa, K., Kim, H.C. and Nabeshima, T.: Role of tumor necrosis factor-α in methamphetamine-induced drug dependence and neurotoxicity. J. Neurosci., 24, 2212-2225 (2004)

  • Nitta, A., Zheng, W.H. and Quirion, R.: Insulin-like growth factor-1 prevents neuronal cell death induced by corticosterone through the activation of the PI3K/Akt pathway. J. Neurosci. Res., 76, 98-103 (2004)

  • Kinukawa, H., Jikou, T., Nitta, A., Furukawa, Y., Hashimoto, M., Fukumitsu, H., Nomoto, H. and Furukawa, S.: Cyclic AMP/protein Kinase A signal attenuates Ca2+-induced fibroblast growth factor-1 synthesis in rat cortical neurons. J. Neurosci. Res., 77, 487-497 (2004)

  • Nitta, A., Nishioka, H., Fukumitsu, H., Furukawa, Y., Sugiura, H., Shen, L. and Furukawa, S.: Hydrophobic dipeptide, Leu-Ile, protects against neuronal death by inducing brain-derived neurotrophic factor and glial cell line-derived neurotrophic synthesis. J. Neurosci. Res., 78, 250-258 (2004)

  • Mizoguchi, H., Yamada, K., Mizuno, M., Mizuno, T., Nitta, A., Noda, Y. and Nabeshima, T.: Regulations of methamphetamine reward by extracellular signal-regulated kinase 1/2/ets-like gene-1 signaling pathway via the activation of dopamine receptors. Mol. Pharmacol., 65, 1293-1301 (2004)

  • Maruyama, W., Nitta, A., Shamoto-Nagai, M., Hirata, Y., Akao, Y., Yodim, M., Furukawa, S., Nabeshima, T. and Naoi, M.: N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor(GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-κB transcription factor. Neurochem. Int., 44, 393-400 (2004)

  • Yamada, Y., Shimizu, K., Nitta, A., Soumiya, H., Fukumitsu, H. and Furukawa, S.: Axonal regrowth downregulates the synthesis of glial cell line-derived neurotrophic factor in the lesioned rat sciatic nerve. Neurosci. Lett., 364, 11-15 (2004)

  • Nagai, T., Yamada, K., Yoshimura, M., Ishikawa, K., Miyamoto, Y., Hashimoto, K., Noda, Y., Nitta, A. and Nabeshima T.: The tissue plasminogen activator-plasmin system participates in the rewarding effect of morphine by regulating dopamine release. Proc. Natl. Acad. Sci. USA., 101, 3650-3655 (2004)

  • Kim, H.C., Yamada, K., Nitta, A., Olariu, A., Tran, M. H., Mizuno, M., Nakajima, A., Nagai, T., Kamei, H., Jhoo, W.K., Im, D.H., Shin, E.J., Hjelle, O.P., Ottersen, O.P., Park, S.C., Kato, K., Mirault, M.E. and Nabeshima, T.: Immunocytochemical evidence that amyloid β(1-42) impairs endogenous antioxidant systems in vivo. Neuroscience, 119, 399-419 (2003)

  • O’Donnell, J., Stemmelin, J., Nitta, A., Brouillette, J. and Quirion, R.: Gene expression profiling following chronic NMDA receptor blockade-induced learning deficits in rats. Synapse, 50, 171-180 (2003)

  • Miyake, K., Yamamoto, W., Tadokoro, M., Takagi, N., Sasakawa, K., Nitta, A., Furukawa, S. and Takeo, S.: Alterations in hippocampal GAP-43, BDNF, and L1 following sustained cerebral ischemia. Brain Res., 935, 24-31 (2002)

  • Murakami, Y., Furukawa, S., Nitta, A. and Furukawa, Y.: Accumulation of nerve growth factor protein at both rostral and caudal stumps in the transected rat spinal cord. J. Neurol. Sci., 198, 63-69 (2002)

  • Sometani, A., Nitta, A., Nomoto, H., Furukawa, Y. and Furukawa, S.: 4-Methylcatechol stimulates phosphorylation of Trk family neurotrophin receptors and MAP kinases in cultured rat cortical neurons. J. Neurosci. Res., 70, 335-339 (2002)

  • Ohmiya, M., Shudai, T., Nitta, A., Nomoto, H., Furukawa, Y. and Furukawa, S.: Brain-derived neurotrophic factor alters cell migration of particular progenitors in the developing mouse cerebral cortex. Neurosci. Lett., 317, 21-24 (2002)

  • Fukuta, T., Nitta, A., Itoh, A., Furukawa, S. and Nabeshima, T.: Difference in toxicity of β-amyloid peptide with aging in relation to nerve growth factor content in rat brain. J. Neural Transm., 108, 221-230 (2001)

  • Ohmiya, M., Fukumitsu, H., Nitta, A., Nomoto, H. and Furukawa, Y.: Administration of FGF-2 to embryonic mouse brain induces hydrocephalic brain morphology and aberrant differentiation of neurons in the postnatal cerebral cortex. J. Neurosci. Res., 65, 228-235 (2001)

  • Sometani, A., Kataoka, H., Nitta, A., Fukumitsu, H., Nomoto, H. and Furukawa, S.: Transforming growth factor-β1 enhances expression of brain-derived neurotrophic factor and its receptor, TrkB, in neurons cultured from rat cerebral cortex. J. Neurosci. Res., 66, 369-376 (2001)

  • Fukumitsu, H., Ohmiya, M., Nitta, A., Furukawa, S., Mima, T. and Mori, K.: Aberrant expression of neurotrophic factors in the ventricular progenitor cells of infant congenitally hydrocephalic NTX rats. Childs Nerv. Syst., 16, 516-521 (2000)

  • Kawakami, H., Nitta, A., Matsuyama, Y., Kamiya, M., Satake, K., Sato, K., Kondou, K., Iwata, H. and Furukawa, S.: Increase in neurotrophin-3 expression followed by Purkinje cell degeneration in the adult rat cerebellum after spinal cord transection. J. Neurosci. Res., 62, 668-674 (2000)

  • Ikemoto, A., Nitta, A., Furukawa, S., Ohnishi, M., Nakamura, A., Fujii, Y. and Okuyama, H.: Dietary n-3 fatty acid deficiency decreases nerve growth factor content in rat hippocampus. Neurosci. Lett., 285, 99-102 (2000)

  • Furukawa, S., Nitta, A. and Furukawa, Y.: Stimulation of neurotrophin synthesis by 4-methycatechol: a promosing approach to the treatment of neurodegeneration. Biomedical Reviews, 10, 45-54 (1999)

  • Itoh, A., Akaike, T., Sokabe, M., Nitta, A., Iida, R., Olariu, A., Yamada, K. and Nabeshima, T.: Impairments of long-term potentiation in hippocampal slices of β-amyloid-infused rats. Eur. J. Pharmacol., 382, 167-175 (1999)

  • Mizuma, H., Takagi, K., Miyake, K., Takagi, N., Ishida, K., Takeo, S., Nitta, A., Nomoto, H., Furukawa, Y. and Furukawa, S.: Microsphere embolism-induced elevation of nerve growth factor level and appearance of nerve growth factor immunoreactivity in activated T-lymphocytes in the rat brain. J. Neurosci. Res., 55, 749-761 (1999)

  • Nitta, A., Ohmiya, M., Sometani, A., Itoh, M., Nomoto, H., Furukawa, Y. and Furukawa, S.: Brain-derived neurotrophic factor prevents neuronal cell death induced by corticosterone. J. Neurosci. Res., 57, 227-235 (1999)

  • Nitta, A., Ito M., Fukumitsu, H., Ohmiya, M., Ito, H., Sometani, A., Nomoto, H., Furukawa, Y. and Furukawa, S.: 4-methylcatechol increases brain-derived neurotrophic factor content and mRNA expression in cultured brain cells and in the brain in vivo. J. Pharmcol. Exp. Ther., 291, 1276-1283 (1999)

  • Nitta, A., Ohmiya, M., Jin-nouchi, T., Sometani, A., Asami, T., Fukumitsu, H., Nomoto, H. and Furukawa, S.: Endogenous neurotrophin-3 is retrogradely transported in the rat sciatic nerve. Neuroscience, 88, 679-685 (1999)

  • Fukumitsu, H., Ohmiya, M., Sometani, A., Nitta, A., Nomoto, H., Furukawa, Y. and Furukawa, S.: Induction of a physiologically active brain-derived neurotrophic factor in the infant rat brain by peripheral administration of 4-methylcatechol. Neurosci. Lett., 274, 115-118 (1999)

  • Ghelardini, C., Galeotti, N., Bartolini, A., Furukawa, S., Nitta, A., Manetti, D. and Gualtieri, F.: Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the acetylcholine releaser PG-9. Jpn. J. Pharmacol., 78, 245-251 (1998)

  • Furukawa, S., Sugihara, Y., Iwasaki, F., Fukumitsu, H., Nitta, A., Nomoto, H. and Furukawa, Y.: Brain-derived neurotrophic factor-like immunoreactively in the adult rat central nervous system predominantly distributed in neurons with substantial amounts of brain-derived neurotrophic factor messenger RNA or responsiveness to brain-derived neurotrophic factor. Neuroscience, 82, 653-670 (1998)

  • Fukumitsu, H., Furukawa, Y., Tsusaka, M., Kinukawa, H., Nitta, A., Nomoto, H., Mima, T. and Furukawa, S.: Simultaneous expression of brain-derived neurotrophic factor and neurotrophin-3 in cajal-retzius, subplate and ventricular progenitor cells during early development stages of the rat cerebral cortex. Neuroscience, 84, 115-127 (1998)

  • Itoh, A., Nitta, A., Hirose, M., Hasegawa, T. and Nabeshima, T.: Effects of metrifonate on impairment of learning and dysfunction of cholinergic neuronal system in basal forebrain-lesioned rats. Behav. Brain Res., 83, 165-167 (1997)

  • Nitta, A., Ogihara, Y., Onishi, J., Hasegawa, T., Furukawa, S. and Nabeshima, T.: Oral administration of propentofylline, a stimulator of nerve growth factor (NGF) synthesis, recovers cholinergic neuronal dysfunction induced by the infusion of anti-NGF antibody into the rat septum. Behav. Brain Res., 83, 201-204 (1997)

  • Itoh, A., Nitta, A., Katono, Y., Usui, M., Naruhashi, K., Iida, R., Hasegawa, T. and Nabeshima, T.: Effects of metrifonate on memory impairment and cholinergic dysfunction in rats. Eur. J. Pharmacol., 322, 11-19 (1997)

  • Nitta, A., Fukuta, T., Hasegawa, T. and Nabeshima, T.: Continuous infusion of β-amyloid protein into the rat cerebral ventricle induces learning impairment and neuronal and morphological degeneration. Jpn. J. Pharmacol., 73, 51-57 (1997)

  • Nitta, A., Fukumitsu, H., Kataoka, H., Nomoto, H. and Furukawa, S.: Administration of corticosterone alters intracellular localization of brain-derived neurotrophic factor-like immunoreactivity in the rat brain. Neurosci. Lett., 226, 115-118 (1997)

  • Fukumitsu, H., Ohashi, A., Nitta, A., Nomoto, H. and Furukawa, S.: BDNF and NT-3 modulate expression and threonine phospherylation of microtubule-associated protein 2 analogues, and alter their distribution in the developing rat cerebral cortex. Neurosci. Lett., 238, 107-110 (1997)

  • Nitta, A., Naruhashi, K., Umemura, M., Hasegawa, T., Furukawa, H., Sekiguchi, F., Ishibashi, K. and Nabeshima, T.: Age-related changes in learning and memory and cholinergic neuronal function in senescence accelerated mice (SAM). Behav. Brain Res., 72, 49-55 (1996)

  • Nitta, A., Ogihara, Y., Onishi, J., Hasegawa, T., Furukawa, S. and Nabeshima, T.: Propentofylline prevents neuronal dysfunction induced by infusion of anti-nerve growth factor antibody into the rat septum. Eur. J. Pharmacol., 307, 1-6 (1996)

  • Itoh, A., Nitta, A., Nadai, M., Nishimura, K., Hirose, M., Hasegawa, T. and Nabeshima, T.: Dysfunction of cholinergic and dopaminergic neuronal systems in β-amyloid protein-infused rats. J. Neurochem., 66, 1113-1117 (1996)

  • Yamada, K., Nitta, A., Saito, T., Hu, J. and Nabeshima, T.: Changes in ciliary neurotrophic factor content in the rat brain after continuous intracerebroventricular infusion of β-amyloid (1-40) protein. Neurosci. Lett., 201, 155-158 (1995)

  • Nitta, A., Furukawa, Y., Hayashi, K., Hasegawa, T. and Nabeshima, T.: Nerve growth factor content of rat brain increases following basal-forebrain lesions induced by ibotenic acid but not by electrolysis. Biol. Pharm. Bull., 17, 34-38 (1994)

  • Nabeshima, T., Nitta, A., Fuji, K., Kameyama, T. and Hasegawa, T.: Oral administration of NGF synthesis stimulators recovers reduced brain NGF content in aged rats and cognitive dysfunction in basal-forebrain-lesioned rats. Gerontology, 40 (Suppl. 2), 46-56 (1994)

  • Nabeshima, T., Itoh, A., Kobayashi, K., Morita, S., Mizuguchi, T., Sawada, H., Nitta, A., Hasegawa, T., Hayashi, K. and Nagatsu, T.: Effects of subacute administration of methamphetamine and nicotine on locomotor activity in transgenic mice expressing the human tyrosine hydroxylase gene. J. Neural Transm. (Gen. Sect.), 97, 41-49 (1994)

  • Nitta, A., Murakami, Y., Furukawa, Y., Kawatsura, W., Hayashi, K., Yamada, K., Hasegawa, T. and Nabeshima, T.: Oral administration of idebenone induces nerve growth factor in the brain and improves learning and memory in basal forebrain-lesioned rats. Naunyn Schmiedebergs Arch. Pharmacol., 349, 401-407 (1994)

  • Nitta, A., Itoh, A., Hasegawa, T. and Nabeshima, T.: β-Amyloid protein-induced Alzheimer’s disease animal model. Neurosci. Lett., 170, 63-66 (1994)

  • Nitta, A., Katono, Y., Itoh, A., Hasegawa, T. and Nabeshima, T.: Nicotine reverses scopolamine-induced impairment of performance in passive avoidance task in rats through its action on the dopaminergic neuronal system. Pharmacol. Biochem, Behav., 49, 807-812 (1994)

  • Nabeshima, T. and Nitta, A.: Memory impairment and neuronal dysfunction induced by β-amyloid protein in rats. Tohoku J. Exp. Med., 174, 241-249 (1994)

  • Nitta, A., Murase, K., Furukawa, Y., Hayashi, K., Hasegawa, T. and Nabeshima, T.: Effects of oral administration of a stimulator for nerve growth factor synthesis in basal forebrain-lesioned rats. Eur. J. Pharmacol., 250, 23-30 (1993)

  • Nitta, A., Hayashi, K., Hasegawa, T. and Nabeshima, T.: Development of plasticity of brain function with repeated trainings and passage of time after basal forebrain lesions in rats. J. Neural Transm. (Gen. Sect.), 93, 37-46 (1993)

  • Nabeshima, T., Nitta, A. and Hasegawa, T.: Impairment of learning and memory and the accessory symptom in aged rat as senile dementia model (3): Oral administration of propentofylline produces recovery of reduced NGF content in the brain of aged rats. Jpn. J. Psychopharmacol., 13, 89-95 (1993)

  • Nitta, A., Murase, K., Furukawa, Y., Hayashi, K., Hasegawa, T. and Nabeshima, T.: Memory impairment and neural dysfunction after continuous infusion of anti-nerve growth factor antibody into the septum in adult rats. Neuroscience, 57, 495-499 (1993)

  • Nitta, A., Hasegawa, T. and Nabeshima, T.: Oral administration of idebenone, a stimulator of NGF synthesis, recovers reduced NGF content in aged rat brain. Neurosci. Lett., 163, 219-222 (1993)

  • Nitta, A., Furukawa, Y., Hayashi, K., Hiramatsu, M., Kameyama, T., Hasegawa, T. and Nabeshima, T.: Denervation of dopaminergic neurons with 6-hydroxydopamine increases nerve growth factor content in rat brain. Neurosci. Lett., 144, 152-156 (1992)

  • Hasegawa, T., Kuzuya, T., Apichartpichean, R. Nadai, M., Nitta, A., Takagi, K. and Nabeshima, T.: Structure-related inhibitory effect of quinolones on alkyl-xanthine elimination in rats. Pharmacol. Toxicol. 69, 5-8 (1991)