Creation of Novel Pharmaceuticals by Power of Organic Synthesis

Research and education based on synthetic organic chemistry are performed in our laboratory. These are essential for discovery of novel medicines because most of them utilized in the present chemotherapy are synthetic small organic molecules. Discovery of novel medicines is highly depending on the expertise of synthetic chemists even in the genome-based drug discovery, and we believe that the importance of the synthetic organic chemistry in pharmaceutical sciences will be unchanged for some time to come. The task of the present organic synthesis mainly lies on the efficient creation of unprecedented organic molecules having versatile functions in addition to the classical synthetic studies of complex natural products. Thus, abilities for molecular design of novel medicine candidates, syntheses of these designed molecules possessing various structural features and complexity, and development of novel reactions and synthetic methodologies with high originality are undoubtedly required for the progress of synthetic and medicinal chemistry. In the light of such status of the recent synthetic organic chemistry and medicinal chemistry, we are energetically and extensively trying the development of innovative new reactions and synthetic studies for discovery of novel medicines in this laboratory.