2001

Original Papers

1)Glucosamine enhances platelet-derived growth factor-induced DNA synthesis via phosphatidylinositol 3-kinase pathway in rat arotic smooth muscle cells.
Sato A, Sasaoka T, Yamazaki K, Nakamura N, Temaru R, Ishiki M, Takata M, Kishida M, Wada T, Ishihara H, Usui I, Urakaze M, Kobayashi M.
Atherosclerosis, 157:341-352, 2001.

2)Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of Insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.
Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M.
Mol Cell Biol, 21:1633-1646, 2001.

3)Reduction of incretin-like salivatin in saliva from patients with type2 diabetes and in parotid glands of streptozotocin-diabetic BALB/c mice.
Kimura I, Sasamoto H, Sasamura T, Sugihara Y, Ohgaku S, Kobayashi M.
Diabetes, Obesity and Metabolism, 3:254-258, 2001.

4)Pioglitazone ameliorates tumor necrosis factor-α-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator-activated receptor-γ.
Iwata M, Haruta T, Usui I, Takata Y, Takano A, Uno T, Kawahara J, Ueno E, Sasaoka T, Ishibashi O, Kobayashi M.
Diabetes, 50:1083-1092, 2001.

5)Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes.
Takano A, Haruta T, Iwata M, Usui I, Uno T, Kawahara J, Ueno E, Sasaoka T, Kobayashi M.
Diabetes, 50:1891-1900, 2001.

6)Potential role of Gab1 and phospholipase C-γ in osmotic shock-induced glucose uptake in 3T3-L1 adipocytes.
Ueno E, Haruta T, Uno T, Usui I, Iwata M, Takano A, Kawahara J, Sasaoka T, Ishibashi O, Kobayashi M.
Horm Metab Res, 33:402-406, 2001.

7)SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes.
Sasaoka T, Hori H, Wada T, Ishiki M, Haruta T, Ishihara H, Kobayashi M.
Diabetologia, 44:1258-1267, 2001.

8)Tyrosine phosphorylation dependent and independent role of Shc in the regulation of IGF-1 induced mitogenesis and glycogen synthesis.
Sasaoka T, Ishiki M, Wada T, Hori H, Hirai H, Haruta T, Ishihara H, Kobayashi M.
Endocrinology, 142:5226-5235, 2001.

9)Strategies to identify new compounds and pharmacological activities from traditional herbal medicines in single and combined usage (Book).
Kimura I, Kimura M.
Pharmacology and Therapeutics in the New Millennium, ed by S K Gupta, M/S Narosa Publishing House, pp 336-344, 2001.

10) New triterpens, myrrhanol A and myrrhanone A, from Guggul-Gum Resins, and their potent anti-inflammatory effect on adjuvant-induced air-pouch granuloma of mice.
Kimura I, Yoshikawa M, Kobayashi S, Sugihara Y, Suzuki M, Oominami H, Murakami T, Matsuda H, Doiphode VV.
Bioorganic Med Chem Lett, 11:985-989, 2001.