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Department of Cancer Cell Biology, University of Toyama

研究業績

主要論文リスト
薬物代謝酵素
Udomsuk L., Jarukamjorn K., Putalun W., Sakuma T., Kawasaki Y. and Nemoto N.:
Modified expression of aryl hydrocarbon receptor-related genes by deoxymiroestrol, a phytoestrogen, in mouse hepatocytes in primary culture.
J. Ethnopharmacol., 137: 902-908, 2011. [Abstract]
Bhadhprasit W., Sakuma T., Kawasaki Y. and Nemoto N.:
Hepatocyte nuclear factor 4 alpha regulates expression of the mouse female-specific Cyp3a41 gene in the liver.
Drug Metab. Dispos., 39: 490-497, 2011. [Abstract]
Chatuphonprasert W., Kondo S., Jarukamjorn K., Kawasaki Y., Sakuma T. and Nemoto N.:
Potent modification of inducible CYP1A1 expression by flavonoids.
Biol. Pharm. Bull., 33: 1698-1703, 2010. [Abstract]
Kawasaki Y., Sakuma T., Goto Y. and Nemoto N.:
Regulatory xenobiotic responsive elements in the distal 5'-flanking region of the mouse Cyp1a2 gene required for transcriptional activation by 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Drug. Metab. Dispos., 38: 1640-1643, 2010. [Abstract]
Jarukamjorn K., Kondo S., Chatuphonprasert W., Sakuma T., Kawasaki Y. and Nemoto N.:
Gender-associated modulation of inducible CYP1A1 expression by andrographolide in mouse liver.
Eur. J. Pharm. Sci., 39: 394-401, 2010. [Abstract]
Hashita T., Sakuma T., Akada M., Nakajima A., Yamahara H., Ito S., Takesako H. and Nemoto N.:
Forkhead box A2-mediated regulation of female-predominant expression of the mouse Cyp2b9 gene.
Drug Metab. Dispos., 36: 1080-1087, 2008. [Abstract]
Sakuma T., Bhadhprasit W., Hashita T. and Nemoto N.:
Synergism of glucocorticoid hormone with growth hormone for female-specific mouse Cyp3a44 gene expression.
Drug Metab. Dispos., 36: 878-884, 2008. [Abstract]
Jaruchotikamol A., Jarukamjorn K., Sirisangtrakul W., Sakuma T., Kawasaki Y. and Nemoto N.:
Strong synergistic induction of CYP1A1 expression by andrographolide plus typical CYP1A inducers in mouse hepatocytes.
Toxicol. Appl. Pharmacol., 224: 156-162, 2007. [Abstract]
Bhadhprasit W., Sakuma T., Hatakeyama N., Fuwa M., Kitajima K. and Nemoto N.:
Involvement of glucocorticoid receptor and pregnane X receptor in the regulation of mouse CYP3A44 female-predominant expression by glucocorticoid hormone.
Drug Metab. Dispos., 35: 1880-1885, 2007. [Abstract]
Jarukamjorn K., Sakuma T., Jaruchotikamol A., Ishino Y., Oguro M. and Nemoto N.:
Modified expression of cytochrome P450 mRNAs by growth hormone in mouse liver.
Toxicology, 219: 97-105, 2006. [Abstract]
Sakuma T., Kitajima K., Nishiyama M., Mashino M., Hashita T. and Nemoto N.:
Suppression of female-specific murine Cyp2b9 gene expression by growth or glucocorticoid hormones.
Biochem. Biophys. Res. Commun., 323: 776-781, 2004. [Abstract]
Sakuma T., Kitajima K., Nishiyama M., Endo Y., Miyauchi K., Jarukamjorn K. and Nemoto N.:
Collaborated regulation of female-specific murine Cyp3a41 gene expression by growth and glucocorticoid hormones.
Biochem. Biophys. Res. Commun., 314: 495-500, 2004. [Abstract]
Uchida Y-I., Yano A., Kumakura S-I., Sakuma T. and Nemoto N.:
Enhancer elements in the mouse Cyp1a2 gene for constitutive expression.
Biochem. Biophys. Res. Commun., 297: 1297-1301, 2002. [Abstract]
Sakuma T., Endo Y., Mashino M., Kuroiwa M., Ohara A., Jarukamjorn K. and Nemoto N.:
Regulation of the expression of two female-predominant CYP3A mRNAs (CYP3A41 and CYP3A44) in mouse liver by sex and growth hormones.
Arch. Biochem. Biophys., 404: 234-242, 2002. [Abstract]
Sakuma T., Honma R., Maguchi S., Tamaki H. and Nemoto N.:
Different expression of hepatic and renal cytochrome P450s between streptozotocin-induced diabetic mice and rats.
Xenobiotica, 31: 223-237, 2001. [Abstract]
Jarukamjorn K., Sakuma T., Yamamoto M., Ohara A. and Nemoto N.:
Sex-associated expression of the mouse hepatic and renal CYP2B enzymes by glucocorticoid hormone.
Biochem. Pharmacol., 62: 161-169, 2001. [Abstract]
Sakuma T., Takai M., Endo Y., Kuroiwa M., Ohara A., Jarukamjorn K., Honma R. and Nemoto N.:
A novel female-specific member of the CYP3A subfamily in the mouse liver.
Arch. Biochem. Biophys., 377: 153-162, 2000. [Abstract]
Sakuma T., Ohtake M., Katsurayama Y., Jarukamjorn K. and Nemoto N.:
Induction of CYP1A2 by phenobarbital in the livers of arylhydrocarbon-responsive and -nonresponsive mice.
Drug Metab. Dispos., 27: 379-384,1999. [Abstract]